Sports in Hypertension of the Elderly
NCT00315224 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 54
Last updated 2006-04-18
Summary
The present work examines the impact of pulse pressure as a footprint of vascular ageing on cardiovascular benefits of endurance training in elderly hypertensives. METHODS AND RESULTS: 54 patients ≥ 60 years with antihypertensive treatment and diastolic 24h-ambulatory blood pressure (ABP) ≤ 90 mmHg are randomly assigned to sedentary activity or a heart-rate controlled 12 week exercise program, consisting of walking on a treadmill at target lactate concentrations of 2.5 ± 0.5 mmol/l. 24h-ambulatory blood pressure, physical performance, arterial elasticity, endothelium-derived vasodilation, quality of life, and weight are assessed at baseline and follow-up.
Conditions
Interventions
- BEHAVIORAL
-
heart-rate controlled 12 week exercise program
Sponsors & Collaborators
-
Charite University, Berlin, Germany
lead OTHER
Principal Investigators
-
Timm H Westhoff, MD · Charité, Campus Benjamin Franklin, Medizinische Klinik IV, Berlin, Germany
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- PARALLEL
Eligibility
- Min Age
- 61 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2005-02-28
- Completion
- 2005-10-31
Countries
- Germany
Study Locations
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