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A Comparison of the Addiction Liability of Hydrocodone and Sustained Release Morphine

NCT00314340 · Status: COMPLETED · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 12

Last updated 2017-05-30

Study results available
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Summary

Characterize the relative abuse liability of a short versus a long acting opioid in chronic pain patients.

Conditions

Interventions

BEHAVIORAL

Markers of Abuse Liability, Neuropsych Testing, and Cue Reactivity

The first dose of the study medication was taken following collection of baseline measurements, and subsequent measurements were taken hourly thereafter. Respiration, heart rate, arterial oxygen saturation (pulse oximetry), and blood pressure were also monitored at these intervals to insure the safety of subjects.

DRUG

ER Morphine

DRUG

hydrocodone plus acetaminophen

DRUG

placebo

Sponsors & Collaborators

  • University of California, Davis

    lead OTHER

Principal Investigators

  • Barth L Wilsey, MD · University of California, CA Medical Center Division of Pain Medicine

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
TRIPLE
Model
CROSSOVER

Eligibility

Min Age
18 Years
Max Age
70 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2005-11-30
Primary Completion
2008-04-30
Completion
2008-04-30

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Entities

Drugs
Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00314340 on ClinicalTrials.gov