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Behavioral Naltrexone Therapy: A Novel Treatment for Heroin Dependence

NCT00332228 · Status: COMPLETED · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 125

Last updated 2012-10-26

No results posted yet for this study

Summary

The overall goal of this research project is to test the efficacy of a newly developed therapy, Behavioral Naltrexone Therapy (BNT), to enhance the success of naltrexone maintenance and long-term abstinence for individuals with heroin dependence. This study includes free detox and outpatient treatment for opioid dependence that includes medication and a behavioral intervention.

Conditions

  • Opiate Dependence

Interventions

DRUG

depot naltrexone

long-acting depot parenteral formulation of naltrexone

BEHAVIORAL

Compliance enhancement (CE)

Compliance enhancement (CE), simulating standard treatment with oral naltrexone

DRUG

BNT

behavioral therapy with oral naltrexone maintenance for the treatment of heroin addiction

Sponsors & Collaborators

  • National Institute on Drug Abuse (NIDA)

    collaborator NIH

  • New York State Psychiatric Institute

    lead OTHER

Principal Investigators

  • Edward Nunes, MD · Columbia University

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Model
FACTORIAL

Eligibility

Min Age
18 Years
Max Age
60 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2002-06-30
Primary Completion
2007-12-31
Completion
2007-12-31

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00332228 on ClinicalTrials.gov