Study of Nesiritide in Diastolic Heart Failure.
NCT00309868 · Status: COMPLETED · Phase: PHASE1/PHASE2 · Type: INTERVENTIONAL · Enrollment: 20
Last updated 2014-03-26
Summary
We hypothesize that nesiritide will have favorable effect in decreasing heart filling pressures and echocardiogram studies.
Conditions
- Diastolic Heart Failure
Interventions
- DRUG
-
neseritide
Sponsors & Collaborators
-
Scios, Inc.
collaborator INDUSTRY -
Massachusetts General Hospital
lead OTHER
Principal Investigators
-
Marc J S, MD · Massachusetts General Hospital
Study Design
- Allocation
- NON_RANDOMIZED
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2002-12-31
- Primary Completion
- 2003-12-31
- Completion
- 2003-12-31
More Related Trials
-
A Safety Study Comparing Natrecor (Nesiritide) Versus Dobutamine Therapy for Worsening Congestive Heart Failure
NCT00270400 ·Status: COMPLETED ·Phase: PHASE3
-
An Exploratory Study of Nesiritide in Participants With Acute Heart Failure
NCT00490724 ·Status: COMPLETED ·Phase: PHASE2
-
A Study of Two Doses of Intravenous NATRECOR hBNP (Nesiritide) in Patients With Worsening Congestive Heart Failure Who Have Difficulty Breathing at Rest
NCT00288730 ·Status: COMPLETED ·Phase: PHASE3
-
A Study of Short-Term Outcomes and Economic Impact For Patients With Worsening Congestive Heart Failure When Natrecor (Nesiritide) is Added to Standard-Care Therapy, Compared to Administration of Placebo With Standard-Care Therapy
NCT00270387 ·Status: COMPLETED ·Phase: PHASE3
-
FUSION I Assesses Safety and Tolerability of Two Doses of NATRECOR (Nesiritide) Administered to Patients With Worsening Congestive (Decompensated) Heart Failure Who Are Concurrently Receiving Their Usual Cardiac Medications and Are at High Risk for Hospitalization.
NCT00270361 ·Status: COMPLETED ·Phase: PHASE3
-
A Study to Develop Additional Safety and Clinical Experience With NATRECOR hBNP (Nesiritide) in the Treatment of Patients With Worsening Congestive Heart Failure Who Require Inpatient Intravenous Therapy With Medications That Influence the Tone and Caliber of Blood Vessels
NCT00271557 ·Status: COMPLETED ·Phase: PHASE3
-
A Study Testing the Effectiveness of Nesiritide in Patients With Acute Decompensated Heart Failure
NCT00475852 ·Status: COMPLETED ·Phase: PHASE3
-
A Study Comparing Blood Flow and Clinical and Safety Effects of the Addition of Natrecor (Nesiritide), Placebo or Intravenous Nitroglycerin to Standard Care for the Treatment of Worsening Congestive Heart Failure.
NCT00270374 ·Status: COMPLETED ·Phase: PHASE3
-
Nesiritide and Vo2 Max in Heart Failure Patients
NCT00240084 ·Status: COMPLETED ·Phase: PHASE2
-
Assessment of Biomarkers and Cardiorenal Syndrome in Acute Decompensated Heart Failure With Vasodilator Therapy
NCT00842023 ·Status: COMPLETED ·Phase: PHASE4
-
Cardiac Hormone Replacement With Brain Natriuretic Peptide (BNP) in Heart Failure
NCT00252187 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Natrecor (Nesiritide) in Transplant-Eligible Management of Congestive Heart Failure-TMAC
NCT00338455 ·Status: TERMINATED ·Phase: PHASE2
-
Tadalafil and Nesiritide as Therapy in Pre-clinical Heart Failure
NCT01544998 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Six Months Clinical and Echocardiographic Outcome of ARNI LCZ696 Therapy in HFrEF Patients
NCT03816306 ·Status: COMPLETED
-
Inhaled Sodium Nitrite on Heart Failure With Preserved Ejection Fraction
NCT02262078 ·Status: COMPLETED ·Phase: PHASE2
-
Natriuretic Peptides as a Prognostic and Risk Stratification Tool in Assessment of Valvular Heart Disease
NCT05439369 ·Status: UNKNOWN
-
LV Diastolic Dysfunction Among the Patients With Systolic Heart Failure-clinical Significance and Prognostic Importance.
NCT01115764 ·Status: UNKNOWN
-
Nitrate's Effect on Activity Tolerance in Heart Failure With Preserved Ejection Fraction
NCT02053493 ·Status: COMPLETED ·Phase: PHASE2
-
Neprilysin Inhibition to Reduce Myocardial Fibrosis in Heart Failure With Preserved Ejection Fraction
NCT06536309 ·Status: NOT_YET_RECRUITING ·Phase: PHASE4
-
Role of Sacubitril/Valsartan in the Improvement of Heart Failure With Reduced Ejection Fraction
NCT04397302 ·Status: COMPLETED
-
Safety and Tolerability of Sacubitril/Valsartan in Heart Failure Patient With Reduced Ejection Fraction
NCT05387967 ·Status: COMPLETED ·Phase: PHASE4
-
Acute Effects of Inorganic Nitrite on Cardiovascular Hemodynamics in Heart Failure With Preserved Ejection Fraction
NCT01932606 ·Status: COMPLETED ·Phase: PHASE2
-
Evaluate the Safety and Efficacy of 48-Hour Infusions of HNO (Nitroxyl) Donor in Hospitalized Patients With Heart Failure
NCT03016325 ·Status: COMPLETED ·Phase: PHASE2
-
Evaluation of the Effect of Injectable Neucardin on Cardiac Function and Reversal Ventricular Remodeling in Patients With Chronic Systolic Heart Failure
NCT05949801 ·Status: COMPLETED ·Phase: PHASE3
-
Treatment of Preclinical Hypertrophic Cardiomyopathy With Diltiazem
NCT00319982 ·Status: COMPLETED ·Phase: PHASE2/PHASE3