A Study of the Safety and Efficacy of Follow-up Serial Infusions of Natrecor(Nesiritide) for the Management of Patients With Heart Failure
NCT00091520 · Status: COMPLETED · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 920
Last updated 2011-05-20
Summary
The purpose of this study is to evaluate the efficacy and safety of Nesiritide administered as serial infusions to heart failure (HF) patients in the outpatient setting.
Conditions
- Heart Failure, Congestive
Interventions
- DRUG
-
Nesiritide
Sponsors & Collaborators
-
Scios, Inc.
lead INDUSTRY
Principal Investigators
-
Scios, Inc. Clinical Trial · Scios, Inc.
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- DOUBLE
- Model
- PARALLEL
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2004-04-30
- Completion
- 2006-12-31
More Related Trials
-
A Study to Develop Additional Safety and Clinical Experience With NATRECOR hBNP (Nesiritide) in the Treatment of Patients With Worsening Congestive Heart Failure Who Require Inpatient Intravenous Therapy With Medications That Influence the Tone and Caliber of Blood Vessels
NCT00271557 ·Status: COMPLETED ·Phase: PHASE3
-
An Exploratory Study of Nesiritide in Participants With Acute Heart Failure
NCT00490724 ·Status: COMPLETED ·Phase: PHASE2
-
A Study of Short-Term Outcomes and Economic Impact For Patients With Worsening Congestive Heart Failure When Natrecor (Nesiritide) is Added to Standard-Care Therapy, Compared to Administration of Placebo With Standard-Care Therapy
NCT00270387 ·Status: COMPLETED ·Phase: PHASE3
-
Natrecor (Nesiritide) in Transplant-Eligible Management of Congestive Heart Failure-TMAC
NCT00338455 ·Status: TERMINATED ·Phase: PHASE2
-
Nesiritide and Vo2 Max in Heart Failure Patients
NCT00240084 ·Status: COMPLETED ·Phase: PHASE2
-
Use of Nesiritide in the Management of Acute Diastolic Heart Failure
NCT00083772 ·Status: TERMINATED ·Phase: PHASE4
-
Impact of Nesiritide Infusion for Decompensated Heart Failure in the Emergency Department
NCT00559338 ·Status: COMPLETED ·Phase: PHASE4
-
An Open-label, One-arm, Study to Evaluate the Hemodynamic Changes and Safety of Nesiritide for Acute Decompensated Heart Failure
NCT00813202 ·Status: COMPLETED ·Phase: PHASE3
-
A Study Comparing Blood Flow and Clinical and Safety Effects of the Addition of Natrecor (Nesiritide), Placebo or Intravenous Nitroglycerin to Standard Care for the Treatment of Worsening Congestive Heart Failure.
NCT00270374 ·Status: COMPLETED ·Phase: PHASE3
-
A Study Testing the Effectiveness of Nesiritide in Patients With Acute Decompensated Heart Failure
NCT00475852 ·Status: COMPLETED ·Phase: PHASE3
-
Inhaled Sodium Nitrite on Heart Failure With Preserved Ejection Fraction
NCT02262078 ·Status: COMPLETED ·Phase: PHASE2
-
Nitrate's Effect on Activity Tolerance in Heart Failure With Preserved Ejection Fraction
NCT02053493 ·Status: COMPLETED ·Phase: PHASE2
-
Six Months Clinical and Echocardiographic Outcome of ARNI LCZ696 Therapy in HFrEF Patients
NCT03816306 ·Status: COMPLETED
-
A Study of Continuous Infusions of HNO (Nitroxyl) Donor in Patients With Heart Failure and Impaired Systolic Function
NCT03357731 ·Status: COMPLETED ·Phase: PHASE2
-
Use of a Novel SUBCUTaneous Preparation of Furosemide to Facilitate Early Supported Discharge of Patients With Heart Failure
NCT05419115 ·Status: COMPLETED ·Phase: PHASE2
-
Management of Volume Overload HF Patients by Individual DSR Treatment adJustment-a clinicAl inVestigation of InfusatE2.0
NCT05965934 ·Status: UNKNOWN ·Phase: PHASE1/PHASE2
-
A Trial of HRS-1893 in Patients With Obstructive Hypertrophic Cardiomyopathy
NCT06516068 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
Dose-comparison Study of Prednisone in Heart Failure
NCT01559727 ·Status: COMPLETED ·Phase: PHASE3
-
Effect of KW-3902IV in Combination With IV Furosemide on Renal Function in Subjects With CHF and Renal Impairment
NCT00159614 ·Status: COMPLETED ·Phase: PHASE2
-
Pilot Deprescribing N-of-1 Trials for Beta-blockers in HFpEF
NCT04757584 ·Status: COMPLETED ·Phase: PHASE4
-
Cardiac Hormone Replacement With Brain Natriuretic Peptide (BNP) in Heart Failure
NCT00252187 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Evaluate the Safety and Efficacy of 48-Hour Infusions of HNO (Nitroxyl) Donor in Hospitalized Patients With Heart Failure
NCT03016325 ·Status: COMPLETED ·Phase: PHASE2
-
A Study to Investigate the Safety, Tolerability, Pharmacodynamics and Pharmacokinetics of an Intravenous Solution of JNJ-39588146 or Placebo in Patients With Heart Failure
NCT01120210 ·Status: COMPLETED ·Phase: PHASE2
-
Real-world Research : Assessment of Effect of Combination of Drugs in the Treatment of Heart Failure
NCT06158711 ·Status: NOT_YET_RECRUITING
-
Effect of Carvedilol Rapid Up-Titration in Patients With Heart Failure With Reduced Ejection Fraction
NCT05179070 ·Status: UNKNOWN ·Phase: PHASE4