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Dynamic Light Scattering to Study Crystalline Proteins in Young Normal Lenses

NCT00304967 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 30

Last updated 2017-07-02

No results posted yet for this study

Summary

This study will use a method called dynamic light scattering (DLS) to study the lens of the eye in young normal subjects. The DLS device uses a very dim laser light to study the lens of the eye. It detects proteins in the lens, identifying early changes that may make the device useful in future cataract studies. This study will use DLS to examine the characteristics of proteins in healthy young lenses that can be used for comparison with lenses in older people and people with cataracts.

Normal volunteers aged 5 to 21 years may be eligible for this study. Participants undergo the following procedures:

Medical history

Eye examination with dilation to include:

* Measurement of visual acuity
* Examination of pupils and eye movements
* Examination of the front of the eye (cornea, lens) with a slit lamp bio-microscope
* Examination of retina with an ophthalmoscope (instrument with a strong light and magnifying lens)
* Dynamic light scattering

Conditions

  • Healthy

Sponsors & Collaborators

  • National Eye Institute (NEI)

    lead NIH

Eligibility

Min Age
5 Years
Max Age
21 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2006-03-15
Completion
2007-03-31

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00304967 on ClinicalTrials.gov