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Clinical Study of Antibacterial Nanoparticles Incorporated in Composite Restorations

NCT00299598 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 10

Last updated 2010-01-06

No results posted yet for this study

Summary

Resin composites withholding antibacterial properties may be useful in preventing recurrent caries. Covalently attached antibacterial polymers are a possible solution.This in vivo study would evaluated the antibacterial effect of alkylated polyethylenimine nanoparticles incorporated into flowable and hybrid composite resin disks embedded in a palatal removable appliance.The disks would be in close contact with the palate in order to check for contact mucosities. disks on the side facing the Tongue would be evaluated for their antibacterial potency with confocal laser scanning microscopy.

Conditions

  • Oral Health

Interventions

DEVICE

alkylated polyethylenimine nanoparticles antibacterial evaluation

Sponsors & Collaborators

  • Hadassah Medical Organization

    lead OTHER

Principal Investigators

  • Ervin I Weiss, DMD · Hadassah Medical Organization

  • Avi Domb, Phd · Hebrew University of Jerusalem

  • Michael M Perez Davidi, DMD · Hadssah Medical Orgenization

  • Nurit Beyth, DMD · Hadassah Medical Organization

Eligibility

Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2006-09-30
Primary Completion
2009-12-31
Completion
2009-12-31

Countries

  • Israel

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00299598 on ClinicalTrials.gov