MedTrace Logo

Prazosin vs. Paroxetine in Combat Stress Symptoms in OIF/OEF Returnees

NCT00261729 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 210

Last updated 2009-12-03

No results posted yet for this study

Summary

Evaluate the efficacy and tolerability of the drug prazosin compared to placebo for combat stress-related nightmares, sleep disturbance and overall function in recently combat-exposed returnees from OIF and OEF. To evaluate the effects of the SSRI paroxetine on behavioral symptoms and overall function in this population.

Conditions

  • Sleep Disorders
  • Stress Disorders, Post-Traumatic

Interventions

DRUG

Paroxetine

paroxetine 20 mg

DRUG

Prazosin

Prazosin

DRUG

placebo

placebo capsules

Sponsors & Collaborators

Principal Investigators

  • Elaine Peskind, MD · VA Puget Sound Health Care System, Seattle

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
QUADRUPLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
50 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2004-07-31
Primary Completion
2007-08-31
Completion
2009-12-31

Countries

  • United States

Study Locations

More Related Trials

Entities

Drugs
Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00261729 on ClinicalTrials.gov