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Molecular Genetic Study of Avascular Necrosis of the Femoral Head

NCT00260897 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 500

Last updated 2007-05-08

No results posted yet for this study

Summary

Avascular necrosis of the femoral head (ANFH) is a debilitating disease that commonly leads to destruction of the hip joint in patients at middle age of life and often requires surgical intervention. Previously, we have identified the collagen type II, alpha 1 (COL2A1) gene as the ANFH disease gene. In this grant proposal, we will establish cell ine and animal models to understand the pathophysiology of ANFH, and extend our ongoing study for identifying genes responsible for non-familiar ANFH by looking into other interacting molecules of the pathway.

Conditions

  • Osteonecrosis

Sponsors & Collaborators

  • National Health Research Institutes, Taiwan

    lead OTHER

Principal Investigators

  • Wei-Ming Chen, M.D. · Department of Orthopaedics and Traumatology, Taipei Veterans General Hospital

Eligibility

Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2003-05-31
Completion
2008-04-30

Countries

  • Taiwan

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00260897 on ClinicalTrials.gov