Genetic Epidemiological Study of Lung Cancer in Taiwan and Clinical Applications

NCT00260871 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 1500

Last updated 2011-07-29

No results posted yet for this study

Summary

Lung adenocarcinoma in Chinese females is hypothesized to be determined by both genetic and environmental factors. In this grant proposal, we propose to map the loci of susceptibility genes of female lung adenocarcinoma based on multiplex families recruited in Taiwan. We focus on a unique pathological type of a unique population in order to reduce heterogeneity of the genetic background. Compared with western women, female Chinese population has a high prevalence of lung adenocarcinoma. Our reasoning is that if we focus on a specific sub-type, which has a familial basis, we will increase the probability of identifying genes associated with female lung adenocarcinoma. The primary goal of this study is to identify the genetic and environmental determinants of female lung adenocarcinoma, and study the relationship between gene polymorphisms and clinical manifestation profiling of lung cancer.

Conditions

Sponsors & Collaborators

  • National Taiwan University Hospital

    collaborator OTHER
  • Taipei Veterans General Hospital, Taiwan

    collaborator OTHER_GOV
  • Chang Gung Memorial Hospital

    collaborator OTHER
  • Taichung Veterans General Hospital

    collaborator OTHER
  • National Cheng-Kung University Hospital

    collaborator OTHER
  • Kaohsiung Medical University

    collaborator OTHER
  • National Health Research Institutes, Taiwan

    lead OTHER

Principal Investigators

  • Chao Hsiung, PhD · NHRI

Eligibility

Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2002-05-31

Countries

  • Taiwan

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Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00260871 on ClinicalTrials.gov