Movement Disorders Caused by Antipsychotic Drugs in Older Patients
NCT00255879 · Status: COMPLETED · Phase: PHASE1 · Type: INTERVENTIONAL · Enrollment: 250
Last updated 2013-06-06
Summary
This study will assess the risk of experiencing tardive dyskinesia and other movement disturbances associated with three atypical antipsychotic drugs among middle-aged and elderly psychiatric patients.
Conditions
- Dyskinesia, Drug-Induced
Interventions
- DRUG
-
Quetiapine
- DRUG
-
Risperidone
- DRUG
Sponsors & Collaborators
-
National Institute of Mental Health (NIMH)
collaborator NIH -
University of California, San Diego
lead OTHER
Principal Investigators
-
Dilip V. Jeste, MD · University of California, San Diego
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- PARALLEL
Eligibility
- Min Age
- 40 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 1999-01-31
- Primary Completion
- 2004-08-31
- Completion
- 2004-08-31
Countries
- United States
Study Locations
More Related Trials
-
Atypical Neuroleptic Drugs in People With Mental Retardation/Developmental Delay
NCT00065273 ·Status: COMPLETED ·Phase: PHASE3
-
Aripiprazole for Neuroleptic-Induced Tardive Dyskinesia
NCT00837707 ·Status: UNKNOWN ·Phase: PHASE4
-
Dopamine D2 and D3 Receptor Occupancy and Clinical Response in Older Patients With Schizophrenia
NCT00825045 ·Status: UNKNOWN ·Phase: NA
-
Switching Medication to Treat Schizophrenia
NCT00044655 ·Status: COMPLETED ·Phase: PHASE4
-
Effectiveness of Atypical Versus Conventional Antipsychotics in Treating Schizophrenia
NCT00237861 ·Status: COMPLETED ·Phase: PHASE4
-
Typical Versus Atypical Antipsychotics; Occupation of Striatal Receptors and the Appearance of Extrapyramidal Symptomatology, in Healthy Volunteers
NCT01259973 ·Status: UNKNOWN ·Phase: PHASE1
-
Effects of Atypical Antipsychotics on Brain Function in Children and Teens With Conduct Disorders
NCT01867398 ·Status: TERMINATED
-
Monitoring of Arrhythmias in Patients Treated With Antipsychotics
NCT04575103 ·Status: UNKNOWN ·Phase: NA
-
Early Predictors of Poor Treatment Response in Patients With Schizophrenia Treated With Atypical Antipsychotics
NCT03730857 ·Status: COMPLETED ·Phase: PHASE1
-
Safety and Tolerability Study of NBI-98854 for the Treatment of Tardive Dyskinesia
NCT02405091 ·Status: COMPLETED ·Phase: PHASE3
-
An Observational Study on Atypical Antipsychotics Long-term Treatment Patients With Schizophrenia
NCT02640911 ·Status: RECRUITING
-
Acute D2 Receptor Blockade Induced Neuronal Network Changes in Human Volunteers
NCT01931059 ·Status: COMPLETED ·Phase: NA
-
Safety and Tolerability of the D1 Dopamine Receptor Antagonist Ecopipam in Patients With Lesch-Nyhan Disease
NCT01065558 ·Status: COMPLETED ·Phase: PHASE1
-
Antipsychotic to Treat Psychosis Syndrome
NCT02137616 ·Status: UNKNOWN ·Phase: NA
-
A Study to Assess Stroke Risk Among Users of Typical Versus Atypical Antipsychotics Stratified by Broad Age Group
NCT04002700 ·Status: COMPLETED
-
Antipsychotic Discontinuation in Alzheimer's Disease
NCT00417482 ·Status: COMPLETED ·Phase: PHASE4
-
Atypical Antipsychotic Treatment Effect On Brain Function In Schizophrenia Measured By FMRI
NCT01234454 ·Status: COMPLETED ·Phase: NA
-
Study to Determine Whether There Are Any Cognitive or Motor Effects From Taking the Medicine Risperidone.
NCT00399698 ·Status: COMPLETED ·Phase: PHASE3
-
A Randomized Double-blind Trial With 6 Antipsychotic Drugs for Schizophrenia
NCT02192723 ·Status: COMPLETED ·Phase: NA
-
Atypical Antipsychotic-induced Mitochondrial Dysfunction in Patients With Schizophrenia
NCT06236451 ·Status: COMPLETED ·Phase: PHASE4
-
A Study to Assess the Clinical Utility of Antipsychotic Medication Levels in Plasma as Determined by Liquid Chromatography-Tandem Mass Spectrometry
NCT02462473 ·Status: TERMINATED ·Phase: PHASE2
-
NBI-98854 for the Treatment of Tardive Dyskinesia in Subjects With Schizophrenia or Schizoaffective Disorder
NCT01393600 ·Status: COMPLETED ·Phase: PHASE2
-
A Study to Compare Disease Progression and Modification Following Treatment With Paliperidone Palmitate Long-Acting Injection or Oral Antipsychotics in Participant's With Recent-onset Schizophrenia or Schizophreniform
NCT02431702 ·Status: COMPLETED ·Phase: PHASE3
-
Research and Evaluation of Antipsychotic Treatment in Community Behavioral Health Organizations
NCT01181960 ·Status: COMPLETED
-
Pharmacogenomics in Autism Treatment
NCT00584701 ·Status: COMPLETED ·Phase: PHASE2/PHASE3