A Randomized Double-blind Trial With 6 Antipsychotic Drugs for Schizophrenia
NCT02192723 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 550
Last updated 2016-07-12
Summary
The purpose of this study is to compare the efficacy and side effects of 6 commonly used antipsychotic drugs in the treatment of schizophrenia in a Chinese population.
Conditions
Interventions
- DRUG
-
Typical antipsychotic
Haloperidol (6\~20mg/day) and perphenazine (16\~64mg/day), twice per day, 8 weeks
- DRUG
-
Risperidone
2\~6mg/day, twice per day, 8 weeks
- DRUG
-
Olanzapine, 400\~750mg/day, twice per day, 8 weeks
- DRUG
-
Quetiapine
Quetiapine, 400~750mg/day, twice per day, 8 weeks
- DEVICE
-
Aripiprazole
Aripiprazole, 10~30mg/day, twice per day, 8 weeks
- DRUG
-
Ziprasidone
Ziprasidone 80\~160mg/day, twice per day, 8 weeks
Sponsors & Collaborators
-
Beijing HuiLongGuan Hospital
lead OTHER
Principal Investigators
-
Zhi-Ren Wang, MD, PhD · Beijing HuiLongGuan Hospital
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- TRIPLE
- Model
- PARALLEL
Eligibility
- Min Age
- 25 Years
- Max Age
- 60 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2012-06-30
- Primary Completion
- 2014-06-30
- Completion
- 2014-06-30
Countries
- China
Study Locations
More Related Trials
-
A Randomized, Open-Label, Multi-Center Study To Evaluate The Efficacy And Safety Of Intramuscular Ziprasidone In Patients With Agitation
NCT00723606 ·Status: COMPLETED ·Phase: PHASE3
-
Pharmacologic Treatment of Acute Episode of Schizophrenia: a Real World Study
NCT03289026 ·Status: COMPLETED ·Phase: PHASE4
-
Standard Comprehensive Intervention to Treat First-episode Schizophrenia
NCT01057849 ·Status: UNKNOWN ·Phase: NA
-
A Study of RO4917838 in Combination With Antipsychotic Treatment in Patients With Schizophrenia.
NCT00616798 ·Status: COMPLETED ·Phase: PHASE2
-
Comparative Study of Aripiprazole, Quetiapine and Ziprasidone in the Treatment of First Episode Nonaffective Psychosis
NCT02305823 ·Status: COMPLETED ·Phase: PHASE4
-
Efficacy and Safety Study of Aripiprazole to Treat Schizophrenia
NCT00202007 ·Status: COMPLETED ·Phase: PHASE2
-
Aripiprazole IM Depot in the Acute Treatment of Adults With Schizophrenia
NCT03172871 ·Status: COMPLETED ·Phase: PHASE3
-
Efficacy and Safety of Ziprasidone to Treat Depressive Symptoms in Patients With Schizophrenia
NCT01260116 ·Status: UNKNOWN
-
Study to Assess the Efficacy, Safety, and Tolerability of AZD8529 in Adult Schizophrenia Patients
NCT00921804 ·Status: COMPLETED ·Phase: PHASE2
-
Comparative Study of Aripiprazole, Quetiapine and Ziprasidone in Treatment of First Episode Psychosis: 3-year Follow-up
NCT02526030 ·Status: COMPLETED ·Phase: PHASE4
-
A Study Comparing the Efficacy and Safety of Ziprasidone and Aripiprazole for the Treatment fo Schizophrenia or Schizoaffective Disorder in Hospitalized Patients
NCT00634348 ·Status: COMPLETED ·Phase: PHASE4
-
The Characteristics of Treatment Resistant Schizophrenia From the Illness Onset
NCT06128408 ·Status: NOT_YET_RECRUITING
-
The Efficacy And Safety Of Intramuscular Ziprasidone For Three Days In Patients With Psychotic Agitation
NCT02935998 ·Status: UNKNOWN ·Phase: PHASE4
-
A Clinical Trial of Lurasidone in Treatment of Schizophrenia
NCT02002832 ·Status: COMPLETED ·Phase: PHASE3
-
A Six-week, Randomized, Double-blind, Placebo-controlled, Parallel Group, Multi-center, Phase II Study
NCT00567710 ·Status: COMPLETED ·Phase: PHASE2
-
Pragmatic RCT Comparing Aripiprazole, Olanzapine and Haloperidol in the Treatment of Schizophrenia
NCT01052389 ·Status: COMPLETED ·Phase: PHASE4
-
Effectiveness of Atypical Versus Conventional Antipsychotics in Treating Schizophrenia
NCT00237861 ·Status: COMPLETED ·Phase: PHASE4
-
Efficacy and Safety of Two Atypical Antipsychotics vs. Placebo in Patients With an Acute Exacerbation of Either Schizophrenia or Schizoaffective Disorder
NCT00061802 ·Status: COMPLETED ·Phase: PHASE4
-
Switching Medication to Treat Schizophrenia
NCT00044655 ·Status: COMPLETED ·Phase: PHASE4
-
Effect And Safety Of Ziprasidone Compared To Other Atypical Antipsychotic Drug In Schizophrenic Patients
NCT00159770 ·Status: COMPLETED ·Phase: PHASE3
-
Efficacy and Safety of Risperidone Oral Solution Combination Clonazepam Versus Haloperidol Intramuscular (IM) Injection for Treatment of Acute Psychotic Agitation in Schizophrenia
NCT00859872 ·Status: COMPLETED ·Phase: PHASE4
-
Study Comparing Antipsychotic Dose Reduction vs. Maintenance Treatment in Patients With Schizophrenia Spectrum Disorder: a Personalized Medicine Approach
NCT07152184 ·Status: NOT_YET_RECRUITING ·Phase: PHASE2
-
Safety and Efficacy of Aripiprazole and Ziprasidone Among Schizophrenic Patients With Metabolic Syndrome
NCT01714011 ·Status: COMPLETED ·Phase: PHASE4
-
A Study to Compare Disease Progression and Modification Following Treatment With Paliperidone Palmitate Long-Acting Injection or Oral Antipsychotics in Participant's With Recent-onset Schizophrenia or Schizophreniform
NCT02431702 ·Status: COMPLETED ·Phase: PHASE3
-
Aripiprazole IM Depot for Chinese Patients With Schizophrenia
NCT03287505 ·Status: COMPLETED ·Phase: PHASE1