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Analysis of Expression of Nitric Oxide Syntheses and Their Functional Role in Human Urothelium

NCT00253006 · Status: TERMINATED · Type: OBSERVATIONAL · Enrollment: 60

Last updated 2006-10-09

No results posted yet for this study

Summary

Painful bladder syndrome (PBS)/interstitial cystitis (IC) may be due to the actions of nitric oxide (NO) in the bladder tissue. NO is a gaseous substance with a very short half-life, synthesized by a group of NO-synthase-enzymes in many tissues.

The goal of this study is to illuminate bladder tissue production of NO in individuals with PBS and healthy individuals, by quantification of NO and NO-enzyme expression by different molecular biological methods.

Conditions

Interventions

PROCEDURE

Tissue examination for protein- and mRNA-expression of NO

Sponsors & Collaborators

  • Zealand University Hospital

    collaborator OTHER

  • Copenhagen University Hospital at Herlev

    lead OTHER

Principal Investigators

  • Pierre Bouchelouche, MD · Roskilde County University Hospital at Koege, Dept. of Clinical Biochemistry

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2006-01-31
Completion
2008-01-31

Countries

  • Denmark

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00253006 on ClinicalTrials.gov