Atrial Tissue Banking: Atrial Tissue Obtained From Patients Undergoing Heart Surgery
NCT00248274 · Status: TERMINATED · Type: OBSERVATIONAL · Enrollment: 300
Last updated 2011-11-22
Summary
Over the past decade, techniques have been refined which permit an enormous amount of information relevant to disease mechanisms to be gained from the examination of heart tissue. The Cardiovascular Institute has extensive experience with these techniques, and has utilized them to examine other heart disease substrates.
In this study, the investigators propose to obtain heart tissue at the time of cardiac surgery which would otherwise be discarded. Their plan is to examine this tissue and correlate their findings with clinical data. Their hope is that the proposed study will provide insight into atrial physiology, including the molecular mechanisms underlying atrial disease and the potential development of atrial fibrillation (AF).
This will be a prospective "registry" for atrial tissue. The investigators propose an enrollment of 300 subjects, to take place at University of Pittsburgh Medical Center (UPMC) Presbyterian over a 5 year period.
Conditions
Sponsors & Collaborators
-
EP Research funds
collaborator UNKNOWN -
University of Pittsburgh
lead OTHER
Principal Investigators
-
David S. Schwartzman, MD · University of Pittsburgh
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2005-01-31
- Primary Completion
- 2009-01-31
- Completion
- 2009-01-31
Countries
- United States
Study Locations
More Related Trials
-
Tissue, Blood and Biomarkers to Predict Future Atrial Fibrillation
NCT03130985 ·Status: COMPLETED
-
A New Operation for the Treatment for Long-standing Atrial Fibrillation
NCT03347695 ·Status: COMPLETED ·Phase: NA
-
Amiodarone Prophylaxis for Atrial Fibrillation in Patients Undergoing Surgery for Lung Cancer
NCT00724581 ·Status: UNKNOWN ·Phase: PHASE4
-
Clinical and Economic Consequences of Left Atrial Bipolar Radiofrequency Ablation of Persistent and Permanent Atrial Fibrillation During Cardiac Surgery
NCT00157807 ·Status: TERMINATED ·Phase: NA
-
Prospective Elimination Of Distal Coronary Sinus-Left Atrial Connections for Atrial Fibrillation Ablation Trial
NCT03646643 ·Status: COMPLETED ·Phase: NA
-
Substrate Ablation and Remodelling in Non-paroxysmal Atrial Fibrillation (AF)
NCT01445925 ·Status: UNKNOWN ·Phase: NA
-
Markers of Oxidative Stress Present in Left Atrial Appendage Tissue in Patients With Atrial Fibrillation
NCT00243802 ·Status: TERMINATED
-
A Retrospective Analysis of the Predictive Potential of Pre-operative
NCT00321282 ·Status: TERMINATED ·Phase: PHASE2
-
Cardiac Monitoring of Post-Operative Cancer Patients Experiencing Atrial Fibrillation
NCT01253590 ·Status: TERMINATED
-
Efficacy of Different Ablation Strategies for Controlling Atrial Fibrillation
NCT00379301 ·Status: COMPLETED ·Phase: NA
-
Atrial Fibrillation (AF) Ablation to Prevent Disease Progression of AF-induced Atrial Cardiomyopathy in Women and Men
NCT06200311 ·Status: RECRUITING ·Phase: NA
-
Bipolar Radiofrequency Ablation -Role in Prevention of Postoperative Atrial Fibrillation
NCT00765089 ·Status: COMPLETED ·Phase: PHASE4
-
Peri-Atrial Inflammatory Fat and Atrial Fibrillation
NCT04186169 ·Status: TERMINATED ·Phase: NA
-
Prolonged Chest Tube Treatment to Reduce Rates of Atrial Fibrillation Following Cardiac Surgery
NCT06800781 ·Status: RECRUITING ·Phase: NA
-
Human Amniotic Membrane to Decrease Post Operative Atrial Fibrillation
NCT04130061 ·Status: COMPLETED ·Phase: EARLY_PHASE1
-
Prevention of Atrial Fibrillation Following Noncardiac Thoracic Surgery
NCT00127712 ·Status: COMPLETED ·Phase: PHASE4
-
Comparative Effectiveness of Different Techniques for Repeat Ablation of Atrial Fibrillation
NCT06988202 ·Status: ENROLLING_BY_INVITATION ·Phase: NA
-
Strategies in Patients Undergoing Repeat AF Ablation
NCT05185310 ·Status: TERMINATED ·Phase: NA
-
Cryoballoon Targeting Atrial Fibrosis in Atrial Fibrillation
NCT03489096 ·Status: WITHDRAWN ·Phase: NA
-
Surgical PA-LAA Shunting: a Feasibility Study
NCT04704791 ·Status: WITHDRAWN ·Phase: NA
-
Evaluation of the Cardioblate CryoFlex Surgical Ablation System in Longstanding Persistent Atrial Fibrillation
NCT01558635 ·Status: TERMINATED ·Phase: NA
-
Renal Nerve Denervation After Pulmonary Vein Isolation for Persistent Atrial Fibrillation
NCT03246568 ·Status: TERMINATED ·Phase: NA
-
Ablation of Ventricular Fibrillation by Accurate Targeting of Arrhythmogenic Regions (AVATAR)
NCT01492764 ·Status: COMPLETED
-
Adjunctive Right Atrial Ablation for Persistent Atrial Fibrillation With Right Atrial Enlargement
NCT05227586 ·Status: COMPLETED
-
Noninvasive 3D Mapping in Persistent Atrial Fibrillation, to Describe Modifications of the Arrhythmogenic Substrate After Pulmonary Vein Isolation and Identify Potential Predicting Factors of Ablation Success
NCT04229160 ·Status: ACTIVE_NOT_RECRUITING ·Phase: NA