Imatinib Mesylate in Treating Patients With Myelofibrosis

NCT00245128 · Status: TERMINATED · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 10

Last updated 2012-01-13

Study results available
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Summary

RATIONALE: Imatinib mesylate may stop the growth of cancer cells by blocking some of the enzymes needed for cell growth.

PURPOSE: This phase II trial is studying the side effects of imatinib mesylate and how well it works in treating patients with myelofibrosis.

Conditions

  • Chronic Myeloproliferative Disorders

Interventions

DRUG

imatinib mesylate

Once daily oral administration of Imatinib Mesylate at a dose of 600mg for 12 months.

Sponsors & Collaborators

  • National Cancer Institute (NCI)

    collaborator NIH
  • OHSU Knight Cancer Institute

    lead OTHER

Principal Investigators

  • Michael Mauro, MD · OHSU Knight Cancer Institute

Study Design

Allocation
NON_RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Model
SINGLE_GROUP

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2005-08-31
Primary Completion
2007-03-31
Completion
2011-10-31

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00245128 on ClinicalTrials.gov