BMS-354825 or Imatinib Mesylate in Treating Patients With Chronic Phase Chronic Myelogenous Leukemia That Did Not Respond to Previous Imatinib Mesylate
NCT00112775 · Status: UNKNOWN · Phase: PHASE2 · Type: INTERVENTIONAL
Last updated 2011-06-07
Summary
RATIONALE: BMS-354825 and imatinib mesylate may stop the growth of cancer cells by blocking some of the enzymes needed for cell growth.
PURPOSE: This randomized phase II trial is studying BMS-354825 to see how well it works compared to imatinib mesylate in treating patients with chronic phase chronic myelogenous leukemia that did not respond to previous imatinib mesylate.
Conditions
Interventions
- DRUG
- DRUG
-
imatinib mesylate
Sponsors & Collaborators
-
National Cancer Institute (NCI)
collaborator NIH -
Jonsson Comprehensive Cancer Center
lead OTHER
Principal Investigators
-
Ronald Paquette, MD · Jonsson Comprehensive Cancer Center
Study Design
- Purpose
- TREATMENT
- Masking
- NONE
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2005-03-31
Countries
- United States
Study Locations
More Related Trials
-
Imatinib Mesylate and Decitabine in Treating Patients With Chronic Myelogenous Leukemia
NCT00054431 ·Status: COMPLETED ·Phase: PHASE2
-
A Study Investigating the Predictive Value of Philadelphia Positive Stem Cell Properties in Newly Diagnosed Patients With Chronic Myeloid Leukemia in Chronic Phase Receiving Treatment With Imatinib
NCT01215487 ·Status: COMPLETED
-
Exploratory Study of IMATINIB High Dose in Intermediate Risk Chronic Myeloid Leukemia in Chronic Phase
NCT00510926 ·Status: COMPLETED ·Phase: PHASE2
-
Imatinib Mesylate and Combination Chemotherapy With or Without a Donor Stem Cell Transplant in Treating Patients With Newly Diagnosed Acute Lymphoblastic Leukemia
NCT00618501 ·Status: COMPLETED ·Phase: PHASE2
-
Interferon Alfa and Imatinib Mesylate in Treating Patients With Chronic Myelogenous Leukemia
NCT00045422 ·Status: COMPLETED ·Phase: PHASE2
-
A Study of Gleevec in Patients With Idiopathic Myelofibrosis or Chronic Myelomonocytic Leukemia (CMML)
NCT00136409 ·Status: COMPLETED ·Phase: PHASE2
-
Efficacy Study of Imatinib Mesylate to Treat Philadelphia-Positive Acute Lymphocytic Leukemia
NCT00154349 ·Status: COMPLETED ·Phase: PHASE2
-
A Prospective Randomized Phase II Study Evaluating the Monitoring of Imatinib Mesylate Plasmatic Through Level in Patients Newly Diagnosed With CP-CML
NCT02896842 ·Status: COMPLETED ·Phase: PHASE2
-
Study of Hyper-CVAD Plus Imatinib Mesylate for Philadelphia-Positive Acute Lymphocytic Leukemia
NCT00038610 ·Status: COMPLETED ·Phase: PHASE2
-
Imatinib Mesylate, Daunorubicin, and Cytarabine in Treating Patients With Relapsed Acute Myeloid Leukemia
NCT00268229 ·Status: COMPLETED ·Phase: PHASE1
-
Imatinib Mesylate and Zoledronic Acid in Patients With Chronic Myeloid Leukaemia in Cytogenetic Response Without Molecular Response
NCT00210119 ·Status: TERMINATED ·Phase: PHASE2
-
Safety and Efficacy of Nilotinib vs. Imatinib in the Treatment of Newly Diagnosed Chinese Ph+ CML-CP Patients
NCT01275196 ·Status: COMPLETED ·Phase: PHASE3
-
A Study to Evaluate Efficacy and Safety of Glinib in Newly Diagnosed CML Patients
NCT02204722 ·Status: TERMINATED ·Phase: PHASE4
-
Imatinib Mesylate in Treating Patients With Advanced Cancer and Liver Dysfunction
NCT00025415 ·Status: COMPLETED ·Phase: PHASE1
-
Imatinib Mesylate and Capecitabine in Treating Patients With Advanced Solid Tumors
NCT00253565 ·Status: COMPLETED ·Phase: PHASE1
-
A Phase II Study of Flumatinib Versus Imatinib to Treat Philadelphia Chromosome Positive Chronic Myelogenous Leukemia
NCT01503502 ·Status: UNKNOWN ·Phase: PHASE2
-
A Study of Imatinib Versus Nilotinib in Adult Patients With Newly Diagnosed Philadelphia Chromosome Positive (Ph+) Chronic Myelogenous Leukemia in Chronic Phase (CML-CP)
NCT00471497 ·Status: COMPLETED ·Phase: PHASE3
-
Effectiveness and Safety Study of Generic Imatinib in Chronic Myeloid Leukemia Patients in Egypt
NCT03454503 ·Status: COMPLETED
-
Investigating Intracellular and Plasma Imatinib Levels in Chronic Myeloid Leukemia
NCT00947830 ·Status: COMPLETED
-
Everolimus and Imatinib Mesylate in Treating Patients With Chronic Phase Chronic Myelogenous Leukemia Who Are Not in Complete Cytogenetic Remission After Previous Imatinib Mesylate
NCT00093639 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Efficacy and Safety of Imatinib Mesylate as First-line Treatment for the Patients With Chronic Phase of Chronic Myeloid Leukemia
NCT02317159 ·Status: UNKNOWN ·Phase: PHASE4
-
TALL-104 and Gleevec in Chronic Myelogenous Leukemia Patients
NCT00415909 ·Status: TERMINATED ·Phase: PHASE2
-
Imatinib (Gleevec(Registered Trademark)) to Treat Chronic Myelomonocytic Leukemia and Atypical Chronic Myelogenous Leukemia
NCT00079313 ·Status: COMPLETED ·Phase: PHASE2
-
S0338, Imatinib Mesylate and Capecitabine in Treating Women With Progressive Stage IV Breast Cancer
NCT00087152 ·Status: COMPLETED ·Phase: PHASE2
-
Imatinib in Combination With Dacarbazine and Capecitabine in Medullary Thyroid Carcinoma
NCT00354523 ·Status: TERMINATED ·Phase: PHASE1/PHASE2