Phase II Study of Imatinib Mesylate in Patients With Life Threatening Malignant Rare Diseases
NCT00154388 · Status: COMPLETED · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 185
Last updated 2016-11-18
Summary
Exploratory study to examine the effect(s) of Imatinib mesylate treatment on life threatening rare diseases with known associations to one or more Imatinib mesylate -sensitive tyrosine kinases, and to identify the contribution of specific protein tyrosine kinases (PTKs) of that specific disease.
Conditions
Interventions
- DRUG
-
Imatinib mesylate
Sponsors & Collaborators
- lead INDUSTRY
Principal Investigators
-
Michael Heinrich, MD · Oregon Health and Science University
Study Design
- Allocation
- NON_RANDOMIZED
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- PARALLEL
Eligibility
- Min Age
- 15 Years
- Max Age
- 70 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2001-02-28
- Primary Completion
- 2007-01-31
- Completion
- 2007-01-31
More Related Trials
-
Efficacy and Safety of Imatinib in Chordoma
NCT00150072 ·Status: COMPLETED ·Phase: PHASE2
-
Imatinib Mesylate in Treating Patients With Myelofibrosis
NCT00245128 ·Status: TERMINATED ·Phase: PHASE2
-
A Phase II Study of Flumatinib Versus Imatinib to Treat Philadelphia Chromosome Positive Chronic Myelogenous Leukemia
NCT01503502 ·Status: UNKNOWN ·Phase: PHASE2
-
Imatinib Mesylate in Treating Patients With Myelofibrosis
NCT00039416 ·Status: COMPLETED ·Phase: PHASE2
-
Imatinib Mesylate After Irinotecan and Cisplatin in Treating Patients With Extensive-Stage Small Cell Lung Cancer
NCT00248482 ·Status: COMPLETED ·Phase: PHASE2
-
Imatinib Mesylate in Treating Patients With Chronic Myelogenous Leukemia
NCT00030394 ·Status: COMPLETED ·Phase: PHASE2
-
Imatinib and PTK787/ZK222584 in Refractory and/or Advanced Solid Tumors
NCT00611689 ·Status: COMPLETED ·Phase: PHASE1
-
Imatinib in Patients With Mucosal or Acral/Lentiginous Melanoma
NCT00424515 ·Status: COMPLETED ·Phase: PHASE2
-
Tumor Tissue Analysis in Patients Receiving Imatinib Mesylate for Malignant Glioma
NCT00401024 ·Status: COMPLETED ·Phase: PHASE1
-
Imatinib Mesylate and Interferon Alfa in Treating Patients With Chronic Myelogenous Leukemia
NCT00015847 ·Status: TERMINATED ·Phase: PHASE2
-
Imatinib Mesylate in Treating Patients With Stage III or Stage IV Melanoma That Cannot Be Removed by Surgery
NCT00470470 ·Status: COMPLETED ·Phase: PHASE2
-
The Study of the Efficacy and the Safety of Flumatinib vs Imatinib as First Line Treatment in Patients With CML
NCT02204644 ·Status: COMPLETED ·Phase: PHASE3
-
Combination of Gemcitabine and Imatinib Mesylate in Pemetrexed-pretreated Patients With Pleural Mesothelioma
NCT02303899 ·Status: COMPLETED ·Phase: PHASE2
-
Gemcitabine and Imatinib Mesylate in Treating Patients With Recurrent or Metastatic Non-Small Cell Lung Cancer
NCT00323362 ·Status: TERMINATED ·Phase: PHASE2
-
Imatinib Standard Dose (400 mg/Day) Versus Imatinib High Dose (800 mg/Day)
NCT00514488 ·Status: COMPLETED ·Phase: PHASE3
-
Imatinib Mesylate and Decitabine in Treating Patients With Chronic Myelogenous Leukemia
NCT00054431 ·Status: COMPLETED ·Phase: PHASE2
-
Imatinib Mesylate in Treating Patients With Recurrent Brain Tumor
NCT00049127 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
S0338, Imatinib Mesylate and Capecitabine in Treating Women With Progressive Stage IV Breast Cancer
NCT00087152 ·Status: COMPLETED ·Phase: PHASE2
-
STI571 in Treating Patients With Recurrent Leukemia
NCT00004932 ·Status: COMPLETED ·Phase: PHASE1
-
Phase ll Study of Imatinib Mesylate for the Neoadjuvant Treatment of Patients With Gastrointestinal Stromal Tumors (GIST)
NCT01483014 ·Status: COMPLETED ·Phase: PHASE2
-
Study to Allow Access to Imatinib for Patients Who Are on Imatinib Treatment in a Novartis-sponsored Study and Are Benefiting From the Treatment as Judged by the Investigator
NCT01742299 ·Status: COMPLETED ·Phase: PHASE4
-
Imatinib Mesylate in Treating Patients With Recurrent Malignant Glioma or Meningioma
NCT00010049 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Phase II Clinical Study of Imatinib Mesylate in Patients With Malignant Gastrointestinal Stromal Tumors (Extension Study)
NCT00237172 ·Status: COMPLETED ·Phase: PHASE2
-
Imatinib Mesylate and Capecitabine in Treating Patients With Advanced Solid Tumors
NCT00253565 ·Status: COMPLETED ·Phase: PHASE1
-
Investigating Intracellular and Plasma Imatinib Levels in Chronic Myeloid Leukemia
NCT00947830 ·Status: COMPLETED