Locomotor Experience Applied Post Stroke Trial

Summary

The purpose of this study is to compare two different treatments to improve walking after stroke (or post-stroke).

Conditions

• Stroke

Interventions

BEHAVIORAL

Early locomotor training program

The early locomotor training program is an out-patient program of locomotor training for 36 sessions, 3 times per week, using a body weight support system and stepping on a treadmill and overground training beginning at 2 months post-stroke.

BEHAVIORAL

Late locomotor training program

The late locomotor training program is an out-patient program of locomotor training for 36 sessions, 3 times per week, using a body weight support system and stepping on a treadmill and overground training beginning at 6 months post-stroke.

BEHAVIORAL

Home Exercise Program

Participants in the early home exercise group will receive a non-specific low intensity exercise program beginning at 2 months post stroke.

Sponsors & Collaborators

• National Institute of Neurological Disorders and Stroke (NINDS)

  collaborator NIH

• Duke University

  lead OTHER

Principal Investigators

• Pamela W. Duncan, PhD, PT, FAPTA, FAHA · Professor and Bette Busch Maniscalco, Doctor of Physical Therapy Division, Research Fellow, Department of Community and Family Medicine, Duke Center for Clinical Health Policy Research

• Katherine J. Sullivan, Ph.D., PT · Co-Principal Investigator, Division of Biokinesiology and Physical Therapy, University of Southern California, Los Angeles, California

• Andrea L. Behrman, Ph.D., PT · Co-Principal Investigator, Department of Physical Therapy, Brooks Center for Rehabilitation Studies, University of Florida, and Department of Veteran Affairs Brain Rehabilitation Research Center, Gainesville, Florida

• Stanley P. Azen, Ph.D., · Director Data Management Core, Biostatistics Division, Department of Preventive Medicine, University of Southern California, Los Angeles, California

• Samuel S. Wu, Ph.D. · Lead Biostatistician - Investigator, Department of Epidemiology and Health Policy Research, University of Florida

• Bruce H. Dobkin, MD · Investigator, Department of Neurology, University of California, Los Angeles, California

• Stephen E. Nadeau, MD · Investigator, Geriatric Research, Education and Clinical Center and the Brain Rehabilitation Research Center, Gainesville VA Medical Center, and the Department of Neurology, University of Florida College of Medicine, Gainesville, Fl

Study Design

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

NONE

Model

PARALLEL

Eligibility

Min Age

18 Years

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

2006-04-30

Primary Completion

2010-04-30

Completion

2012-06-30

Countries

• United States

Study Locations