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Herpesvirus in Idiopathic Pulmonary Fibrosis

NCT00228670 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 41

Last updated 2017-05-11

No results posted yet for this study

Summary

The purpose of this study is to: 1) to develop a method to quantify Epstein Barr Virus (EBV) load in lung tissue of humans and to determine whether EBV viral load is significantly higher in lung tissue from patients with idiopathic pulmonary fibrosis (IPF) than in control lung tissue; 2) to determine whether EBV localized to epithelial cells in IPF lungs and to relate epithelial positivity to tissue viral load; 3) to measure viral load in induced sputum from IPF subjects over time in order to determine whether periodic active herpes virus replication occurred in the respiratory tract; and 4) to compare longitudinal measures of viral load in induced sputum with simultaneously collected saliva in order to assess the clinical utility of the two approaches.

Conditions

  • Lung Diseases
  • Herpesvirus Infections

Sponsors & Collaborators

  • Emory University

    lead OTHER

Principal Investigators

  • Arlene Stecenko, MD · Emory University

Eligibility

Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2005-07-31
Primary Completion
2012-08-31
Completion
2012-08-31

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00228670 on ClinicalTrials.gov