MedTrace Logo

The Effects of Acute Administration of Bupropion on Neural Substrates Underlying Hedonic Capacity

NCT00205946 · Status: COMPLETED · Phase: PHASE1 · Type: INTERVENTIONAL · Enrollment: 32

Last updated 2007-12-06

No results posted yet for this study

Summary

The purpose of the study is to evaluate the effects of a single-dose of Wellbutrin XL (bupropion hydrochloride) on reward processing.

Conditions

Interventions

DRUG

Bupropion

150 mg of bupropion administered 5 hours before fMRI scanning

DRUG

Placebo

Administered 5 hours prior to fMRI scanning (randomly assigned, double blind)

Sponsors & Collaborators

  • Massachusetts General Hospital

    collaborator OTHER

  • Affective Neuroscience Laboratory

    lead OTHER

Principal Investigators

  • Diego A Pizzagalli, PhD · Harvard University

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Model
CROSSOVER

Eligibility

Min Age
18 Years
Max Age
64 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2005-04-30
Completion
2007-07-31

Countries

  • United States

Study Locations

More Related Trials

Entities

Drugs
Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00205946 on ClinicalTrials.gov