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Assessment of Early Genetic Changes in Smokers

NCT00200408 · Status: TERMINATED · Type: OBSERVATIONAL · Enrollment: 10

Last updated 2015-04-08

No results posted yet for this study

Summary

This study will look at the genetic profile of cells taken from the oral cavity of healthy college students who smoke and who do not smoke cigarettes. This will be done using a small brush similar to that used in Pap tests for cervical cancer detection. Our aim is to determine if smoking causes early genetic changes in the DNA of these cells such as have been seen in the cells of cancerous tumors of the head and neck area and nearby healthy tissues. This will be correlated with data from subject questionnaires to assess tobacco use, and other behavior and demographic information.

Conditions

  • Cancer of Head and Neck
  • Smoking

Sponsors & Collaborators

  • Montefiore Medical Center

    lead OTHER

Principal Investigators

  • Richard V Smith, MD · Montefiore Medical Center

  • Thomas Belbin, PhD · Albert Einstein College of Medicine

  • Nicholas Schlecht, PhD · Albert Einstein College of Medicine

Eligibility

Min Age
18 Years
Max Age
35 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2004-03-31
Primary Completion
2005-01-31

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00200408 on ClinicalTrials.gov