Paclitaxel, Carboplatin, and Oral Etoposide Followed by Weekly Paclitaxel in High Grade Neuroendocrine Carcinoma
NCT00193531 · Status: COMPLETED · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 100
Last updated 2023-04-11
Summary
carboplatin and etoposide, followed by maintenance therapy with weekly paclitaxel in patients with poorly differentiated neuroendocrine carcinomas. We hope to identify a "standard treatment" for this unusual group of patients who are not usually eligible for clinical trials.
Conditions
- Neuroendocrine Carcinoma
Interventions
- DRUG
- DRUG
- DRUG
-
Etoposide
Sponsors & Collaborators
- collaborator INDUSTRY
-
SCRI Development Innovations, LLC
lead OTHER
Principal Investigators
-
John D. Hainsworth, MD · SCRI Development Innovations, LLC
Study Design
- Allocation
- NON_RANDOMIZED
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 1998-12-31
- Primary Completion
- 2007-01-31
- Completion
- 2007-01-31
More Related Trials
-
Study of Paclitaxel, Carboplatin, and Gemcitabine Versus Gemcitabine and Vinorelbine for Non-Small Cell Lung Cancer
NCT00193362 ·Status: COMPLETED ·Phase: PHASE3
-
Carboplatin Plus Cetuximab for Treatment of Stage IIIB/IV Non-Small Cell Lung Cancer (NSCLC)
NCT00097214 ·Status: COMPLETED ·Phase: PHASE2
-
Study of Everolimus With Paclitaxel and Carboplatin in Patients With Metastatic Melanoma
NCT01014351 ·Status: COMPLETED ·Phase: PHASE2
-
Efficacy/Safety of Imprime PGG With Cetuximab & Paclitaxel/Carboplatin Therapy in Pts With Untreated Advanced Non-Small Cell Lung Cancer
NCT00874848 ·Status: COMPLETED ·Phase: PHASE2
-
A Study Evaluating the Efficacy and the Safety of First-line Chemotherapy Combined With the Therapeutic Vaccine Named TG4010 and Nivolumab in Patients With Advanced Non-squamous Non-Small Cell Lung Cancer (NSCLC)
NCT03353675 ·Status: COMPLETED ·Phase: PHASE2
-
Carboplatin and Etoposide in Combination With Vorinostat for Patients With Extensive Stage Small Cell Lung Cancer
NCT00702962 ·Status: TERMINATED ·Phase: PHASE1/PHASE2
-
A Phase I/II Study of Paclitaxel, Carboplatin and YM155 (Survivin Suppressor) in Subjects With Solid Tumors (Phase I) and Advanced Non-Small Cell Lung Carcinoma (Phase II)
NCT01100931 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Efficacy/Safety of Imprime PGG® Injection With Bevacizumab and Paclitaxel/Carboplatin in Patients With Untreated Advanced Non-Small Cell Lung Cancer (NSCLC)
NCT00874107 ·Status: COMPLETED ·Phase: PHASE2
-
A Study of PRO95780 in Patients With Previously Untreated, Advanced-Stage Non-Small Cell Lung Cancer (APM4074g)
NCT00480831 ·Status: COMPLETED ·Phase: PHASE2
-
A Phase I/II Study of Carboplatin and Etoposide With or Without Obatoclax in Extensive-stage Small Cell Lung Cancer (ES-SCLC)
NCT00682981 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
A Study Evaluating RO5479599 in Combination With Carboplatin and Paclitaxel in Participants With Advanced or Metastatic Non-Small-Cell Lung Cancer (NSCLC) of Squamous Histology
NCT02204345 ·Status: TERMINATED ·Phase: PHASE1/PHASE2
-
Phase 1b/2 Study of Carfilzomib, Carboplatin, and Etoposide in Patients With Previously Untreated Extensive Stage Small-cell Lung Cancer
NCT01987232 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Safety and Efficacy of Carboplatin/Paclitaxel and Carboplatin/Paclitaxel/Bevacizumab With and Without Pictilisib in Previously Untreated Advanced or Recurrent Non-small Cell Lung Cancer
NCT01493843 ·Status: COMPLETED ·Phase: PHASE2
-
S0342: Paclitaxel, Carboplatin, and Cetuximab in Treating Patients With Stage IIIB or Stage IV Non-Small Cell Lung Cancer
NCT00085501 ·Status: COMPLETED ·Phase: PHASE2
-
Phase II Trial of a 96-Hour Continuous Infusion of Paclitaxel Followed by Cisplatin for Patients With Stage III/IV and Relapsed NSCLC
NCT00001450 ·Status: COMPLETED ·Phase: PHASE2
-
Gemcitabine, Carboplatin or Paclitaxel Plus Radiation Therapy in Treating Patients With Stage IIIA or IIIB Non-Small Cell Lung Cancer
NCT00016315 ·Status: COMPLETED ·Phase: PHASE1
-
Carboplatin and Etoposide Plus LBH589 for Small Cell Lung Cancer
NCT00958022 ·Status: TERMINATED ·Phase: PHASE1
-
Study of Carboplatin/Paclitaxel in Combination With ABT-869 in Subjects With Advanced or Metastatic Non-Small Cell Lung Cancer (NSCLC)
NCT00716534 ·Status: COMPLETED ·Phase: PHASE2
-
Carboplatin and Paclitaxel Combined With Cetuximab and/or IMC-A12 in Patients With Advanced Non-Small Cell Lung Cancer
NCT00986674 ·Status: COMPLETED ·Phase: PHASE2
-
Testing the Addition of an Anti-cancer Drug, Entinostat, to the Usual Chemotherapy and Immunotherapy Treatment (Atezolizumab, Carboplatin and Etoposide) for Previously Untreated Aggressive Lung Cancer That Has Spread
NCT04631029 ·Status: COMPLETED ·Phase: PHASE1
-
Carboplatin With Either Paclitaxel Poliglumex or Paclitaxel in Treating Women With Stage IIIB, Stage IV, or Recurrent Non-Small Cell Lung Cancer
NCT00551733 ·Status: TERMINATED ·Phase: PHASE3
-
Nivolumab in Combination With Chemotherapy, or Nivolumab in Combination With Ipilimumab, in Advanced EGFR-Mutant or ALK-Rearranged NSCLC
NCT03256136 ·Status: COMPLETED ·Phase: PHASE2
-
Preoperative or Postoperative Therapy of Patients With Stages IB, II, IIIA Non-Small Cell Lung Cancer
NCT00193310 ·Status: COMPLETED ·Phase: PHASE2
-
Phase II Study of Buparlisib + Docetaxel in Advanced or Metastatic Squamous Non-small Cell Lung Cancer (NSCLC) Patients
NCT01911325 ·Status: TERMINATED ·Phase: PHASE1
-
A Study of Carboplatin Plus Etoposide With or Without Atezolizumab in Participants With Untreated Extensive-Stage (ES) Small Cell Lung Cancer (SCLC)
NCT02763579 ·Status: COMPLETED ·Phase: PHASE3