Enzastaurin for Patients With Metastatic Colorectal Cancer
NCT00192114 · Status: COMPLETED · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 28
Last updated 2020-08-06
Summary
Enzastaurin given daily to participants with colorectal cancer who have Stage 4 disease and have not received prior chemotherapy for advanced colorectal cancer
Conditions
- Colonic Neoplasms
Interventions
- DRUG
-
Enzastaurin HCl
1200 milligrams (mg) loading dose orally, then 500 mg, orally, daily, up to six 28-day cycles.
Sponsors & Collaborators
- lead INDUSTRY
Principal Investigators
-
Call 1-877-CTLILLY (1-877-285-4559) or 1-317-615-4559 Mon - Fri 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST) · Eli Lilly and Company
Study Design
- Allocation
- NA
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 19 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2005-08-31
- Primary Completion
- 2008-03-31
- Completion
- 2008-03-31
Countries
- Denmark
- Sweden
Study Locations
More Related Trials
-
A Study of Encorafenib Plus Cetuximab Taken Together With Pembrolizumab Compared to Pembrolizumab Alone in People With Previously Untreated Metastatic Colorectal Cancer
NCT05217446 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
A Study of EZN-2208 Administered With or Without Cetuximab in Patients With Metastatic Colorectal Carcinoma
NCT00931840 ·Status: UNKNOWN ·Phase: PHASE2
-
Bryostatin 1 in Treating Patients With Metastatic Colorectal Cancer
NCT00003220 ·Status: COMPLETED ·Phase: PHASE2
-
Azacitidine and Entinostat in Treating Patients With Metastatic Colorectal Cancer
NCT01105377 ·Status: COMPLETED ·Phase: PHASE2
-
Rosuvastatin in the Treatment of Rectal Cancer
NCT02569645 ·Status: COMPLETED ·Phase: PHASE2
-
A Phase I/II Study of Combination Immunotherapy for Advanced Cancers Including HPV-Associated Malignancies, Small Bowel, and Colon Cancers
NCT04708470 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE1/PHASE2
-
ZN-c3 in Adult Participants With Metastatic Colorectal Cancer
NCT05743036 ·Status: TERMINATED ·Phase: PHASE1
-
A Study of JNJ-89402638 for Metastatic Colorectal and Gastric Cancers
NCT06663319 ·Status: RECRUITING ·Phase: PHASE1
-
Clinical and Translational Study of STA-9090
NCT01111838 ·Status: COMPLETED ·Phase: PHASE2
-
Efficacy and Safety Study of Recombinant Endostatin Combined With Chemotherapy to Treat Advanced Colorectal Cancer
NCT01529164 ·Status: UNKNOWN ·Phase: PHASE2
-
A Study of Encorafenib Plus Cetuximab With or Without Chemotherapy in People With Previously Untreated Metastatic Colorectal Cancer
NCT04607421 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE3
-
Bortezomib in Treating Patients With Metastatic or Recurrent Colorectal Cancer
NCT00052507 ·Status: COMPLETED ·Phase: PHASE2
-
A Study of Cetuximab in Patients Who Have Stage IV Colorectal Cancer
NCT00055419 ·Status: COMPLETED ·Phase: PHASE2
-
Erlotinib in Treating Patients With Recurrent or Metastatic Colorectal Cancer
NCT00032110 ·Status: COMPLETED ·Phase: PHASE2
-
Irinotecan in Treating Patients With Metastatic Colorectal Cancer
NCT00003544 ·Status: COMPLETED ·Phase: PHASE2
-
Dasatinib in Treating Patients With Previously Treated Metastatic Colorectal Cancer
NCT00504153 ·Status: COMPLETED ·Phase: PHASE2
-
ISIS 2503 in Treating Patients With Metastatic and/or Locally Recurrent Colorectal Cancer
NCT00004193 ·Status: TERMINATED ·Phase: PHASE2
-
Botensilimab, Balstilimab and Regorafenib for the Treatment of Patients With Microsatellite Stable Metastatic Colorectal Cancer Who Have Progressed on Prior Chemotherapy
NCT05672316 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE1/PHASE2
-
Encorafenib, Cetuximab, and Nivolumab in Treating Patients With Microsatellite Stable, BRAFV600E Mutated Unresectable or Metastatic Colorectal Cancer
NCT04017650 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE1/PHASE2
-
Phase II Study of Zaltrap and Chemotherapy for Advanced Resectable Colorectal Cancer
NCT02046538 ·Status: WITHDRAWN ·Phase: PHASE2
-
A Study of Botensilimab and Balstilimab for the Treatment of Colorectal Cancer
NCT05608044 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
Midostaurin (PKC412) for Locally Advanced Rectal Cancer
NCT01282502 ·Status: COMPLETED ·Phase: PHASE1
-
A Phase II Trial Assessing Nivolumab in Class II Expressing Microsatellite Stable Colorectal Cancer
NCT03981146 ·Status: COMPLETED ·Phase: PHASE2
-
Efficacy and Safety of Everolimus in Patients With Metastatic Colorectal Cancer Who Have Failed Prior Targeted Therapy and Chemotherapy
NCT00419159 ·Status: COMPLETED ·Phase: PHASE2
-
An Exploratory Pharmacogenomic Study of Monotherapy Erbitux in Subjects With Metastic Colorectal Cancer
NCT00207155 ·Status: COMPLETED ·Phase: PHASE1