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Contrast-Enhanced US of Spleen, Liver and Kidney

NCT00190281 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 53

Last updated 2005-12-13

No results posted yet for this study

Summary

To evaluate the changes in the microcirculation of the liver, kidney and spleen during acute infection in patients with malaria (cohorts 1 and 3) and other infectious diseases such as acute pyelonephritis at day 0 (within 8 hours of the treatment start), day 2 to 4 and day 28-32, using functional US with continuous infusion of a contrast agent (SonoVue, Bracco, Italy).

Study hypothesis: malaria patients should exhibit a different pattern of enhancement, particularly when quantitative measurements of the SU signals is performed with destruction reperfusion kinetics.

Conditions

Sponsors & Collaborators

  • Assistance Publique - Hôpitaux de Paris

    lead OTHER

Principal Investigators

  • Jean-Michel Correas, MD PhD · NECKER UNIVERSITY HOSPITAL

  • Pierre Buffet, MD PhD · Centre Médical - Institut Pasteur

  • Olivier Lortholary, MD PhD · NECKER UNIVERSITY HOSPITAL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2005-08-31

Countries

  • France

Study Locations

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Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00190281 on ClinicalTrials.gov