ECLAXIR:Search for an Association Between CX3CR1 V249I Polymorphism, Preeclampsia and Endothelial Injury
NCT00190177 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 370
Last updated 2013-10-18
Summary
The study hypothesis is the involvement of the couple CX3CR1/CX3CL1 in occurrence of endothelial injury in preeclampsia. According to this hypothesis, Carriers of the I249 allele who express less CX3CR1 shoud be protected against this risk. The main objective of the study is the search of an association between CX3CR1 V249I polymorphism and preeclampsia. The secondary aims are the search of an association with the most severe forms of preeclampsia and endothelial injury.
Conditions
Sponsors & Collaborators
-
Assistance Publique - Hôpitaux de Paris
lead OTHER
Principal Investigators
-
Laurent Mandelbrot, MD-PhD · Assistance Publique - Hôpitaux de Paris
Eligibility
- Sex
- FEMALE
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2003-03-31
- Primary Completion
- 2007-10-31
- Completion
- 2007-10-31
Countries
- France
Study Locations
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