MedTrace Logo

Diastolic Dysfunction and Atrial Fibrillation in CABG Surgery

NCT00188903 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 250

Last updated 2010-08-05

No results posted yet for this study

Summary

Left ventricular (LV) diastolic dysfunction is a common manifestation of heart disease that is responsible for significant morbidity and mortality.It is present when the ventricular filling is impaired as a result of delayed relaxation or decreased compliance. During Coronary artery bypass grafting (CABG) surgery, LV diastolic dysfunction is a frequent occurrence. Failure of the left ventricle to dilate normally causes an increase in LV filling pressure. Atrial fibrillation (AF) is a common complication after cardiac surgery affecting 20-30% of patients undergoing coronary revascularization procedures. AF is associated with significant morbidity and mortality and has been identified as a causative factor of increased length of both hospital and intensive care unit (ICU) stay after CABG surgery, resulting in increased resource utilization and medical care costs.The primary aim of this study is to determine if patients with preoperative diastolic dysfunction are exposed to higher risk of AF after coronary revascularization surgery.

Conditions

Interventions

PROCEDURE

Diastolic measurements during TEE

Transesophageal echocardiography with diastolic measurements

Sponsors & Collaborators

  • University Health Network, Toronto

    lead OTHER

Principal Investigators

  • George N Djaiani, MD · Toronto General Hospital, Univsersity Health Network

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2004-03-31
Primary Completion
2007-11-30
Completion
2010-03-31

Countries

  • Canada

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00188903 on ClinicalTrials.gov