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Cognitive Function and Fatigue in Colorectal Cancer (CRC) Patients After Chemotherapy

NCT00188331 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 441

Last updated 2016-03-22

No results posted yet for this study

Summary

This is a prospective, longitudinal cohort study to evaluate fatigue and cognitive function in patients with colorectal cancer (CRC) treated with chemotherapy, and in patients with the same malignancy, that do not receive chemotherapy. A self-report questionnaire for fatigue (the FACT-F), and validated tests of cognitive function, will be applied at predetermined times before, during and after chemotherapy, to determine the incidence, severity and duration of these symptoms. Comparisons will be made in changes in cognition for individuals, as well as between the chemotherapy and the control group. Mechanisms that might lead to fatigue and/or cognitive decline will be investigated.

Conditions

  • Cognition
  • Fatigue
  • Colorectal Neoplasm

Interventions

BEHAVIORAL

Neuropsychological Testing

neuropsychological testing with traditional tests, CANTAB and six elements test as well as questionnaires

Sponsors & Collaborators

  • Canadian Cancer Trials Group

    collaborator NETWORK

  • Young Investigator Award - American Society of Clinical Oncologists

    collaborator UNKNOWN

  • Peterborough K.M. Hunter Graduate Studentship

    collaborator UNKNOWN

  • University Health Network, Toronto

    lead OTHER

Principal Investigators

  • Janette Vardy, MD · Princess Margaret Hospital University of Toronto

  • Ian Tannock · Princess Margaret Hospital University of Toronto

Eligibility

Min Age
18 Years
Max Age
75 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2003-11-30
Primary Completion
2015-09-30
Completion
2015-09-30

Countries

  • Australia
  • Canada

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00188331 on ClinicalTrials.gov