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Colorectal Cancer Screening for Cancer Survivors

NCT00982059 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 140

Last updated 2018-01-31

No results posted yet for this study

Summary

The risk of colorectal cancer (CRC) is significant among cancer survivors treated with abdominal radiation therapy (RT). Further, CRC is once of the few cancers for which there is effective screening. Although some expert groups recommend early CRC screening for patients with prior abdominal RT, the effectiveness of early screening is unknown. It is also unknown if radiation-induced CRC passes through a "pre-clinical" phase in which precancerous polyps are detectable and treatable prior to becoming invasive cancers. This study will evaluate whether screening will detect pre-invasive colorectal polyps among survivors treated with RT.

Conditions

Interventions

OTHER

Colonoscopic examination

All patients enrolled in the study will undergo a colonoscopic examination and complete a baseline questionnaire.

Sponsors & Collaborators

  • Princess Margaret Hospital, Canada

    collaborator OTHER

  • University Health Network, Toronto

    lead OTHER

Principal Investigators

  • David Hodgson, MD · University Health Network, Princess Margaret Hospital

  • Andrea K Ng, MD · Dana-Farber Cancer Institute

Eligibility

Min Age
35 Years
Max Age
49 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2008-05-31
Primary Completion
2014-12-31
Completion
2018-01-24

Countries

  • United States
  • Canada

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00982059 on ClinicalTrials.gov