To Evaluate the Safety and Effectiveness of Atorvastatin Plus a Cholinesterase Inhibitor in AD Patients.
NCT00151502 · Status: COMPLETED · Phase: PHASE3 · Type: INTERVENTIONAL · Enrollment: 600
Last updated 2021-02-18
Summary
The purpose of this study is to find out if atovastatin, when taken with a cholinesterase inhibitor, is effective for treating Alzheimer's disease.
Conditions
Interventions
- DRUG
Sponsors & Collaborators
-
Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
lead INDUSTRY
Principal Investigators
-
Pfizer CT.gov Call Center · Pfizer
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- DOUBLE
- Model
- PARALLEL
Eligibility
- Min Age
- 50 Years
- Max Age
- 90 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2002-11-30
- Completion
- 2007-07-31
Countries
- United States
- Australia
- Austria
- Canada
- Denmark
- Germany
- South Africa
- Spain
- Sweden
- United Kingdom
Study Locations
More Related Trials
-
Clinical- and Immunological Activity, Safety and Tolerability of Different Doses / Formulations of AFFITOPE AD02 in Early Alzheimer's Disease
NCT01117818 ·Status: COMPLETED ·Phase: PHASE2
-
Study Evaluating the Safety, Tolerability and Efficacy of PBT2 in Patients With Early Alzheimer's Disease
NCT00471211 ·Status: COMPLETED ·Phase: PHASE2
-
Safety and Tolerability Study Evaluating a New Treatment for Subjects With Mild to Moderate Alzheimer's Disease
NCT01690195 ·Status: TERMINATED ·Phase: PHASE2
-
Multiple Dose Safety Study of NPT088 in Patients With Mild to Moderate Probable Alzheimer's Disease
NCT03008161 ·Status: COMPLETED ·Phase: PHASE1
-
Tolerability and Safety of Subcutaneous Administration of Affitope AD01 in Mild to Moderate Alzheimer's Disease
NCT00495417 ·Status: COMPLETED ·Phase: PHASE1
-
A Phase 1 Study of the Safety, Tolerability and Pharmacokinetics of ABT-126 in Subjects With Alzheimer's Disease
NCT01482845 ·Status: COMPLETED ·Phase: PHASE1
-
A Study to Evaluate the Efficacy and Safety of MK-1167 in Participants With Alzheimer's Disease Dementia (MK-1167-008)
NCT06721156 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
A Study of SB-742457, Added to Donepezil for the Treatment of Mild-to-moderate Alzheimer's Disease
NCT00710684 ·Status: COMPLETED ·Phase: PHASE2
-
A Study of the Safety and Tolerability of ASP0777 in Subjects With Alzheimer's Disease (AD) Taking a Stable Dose of Donepezil
NCT01406145 ·Status: COMPLETED ·Phase: PHASE1
-
Preliminary Efficacy and Safety Study of ST101 Plus Aricept in Alzheimer's Disease
NCT00842816 ·Status: COMPLETED ·Phase: PHASE2
-
Efficacy and Safety of AD-35 in Treatment of Subjects With Mild to Moderate Alzheimer's Disease
NCT03625401 ·Status: UNKNOWN ·Phase: PHASE2
-
Safety and Tolerability Study in Patients With Mild to Moderate Alzheimer's Disease (AD)
NCT00411580 ·Status: COMPLETED ·Phase: PHASE1
-
A Trial of the Safety, Tolerability, and Pharmacodynamics of CVL-871 in Subjects With Dementia-Related Apathy
NCT04958031 ·Status: TERMINATED ·Phase: PHASE2
-
Study to Evaluate the Efficacy and Safety of GSK239512 in Alzheimer's Disease
NCT01009255 ·Status: COMPLETED ·Phase: PHASE2
-
Safety and Efficacy Study of ABT-089 in Adults With Mild to Moderate Alzheimer's Disease
NCT00555204 ·Status: TERMINATED ·Phase: PHASE2
-
Tolerability and Safety of Subcutaneous Administration of AFFITOPE AD02 in Mild to Moderate Alzheimer's Disease
NCT00633841 ·Status: COMPLETED ·Phase: PHASE1
-
Safety and Efficacy Study Evaluating TRx0237 in Subjects With Mild to Moderate Alzheimer's Disease
NCT01689246 ·Status: COMPLETED ·Phase: PHASE3
-
Efficacy, Safety, & Tolerability of AZD3480 Patients With Mild to Moderate Dementia of the Alzheimer's Type (AD)
NCT01466088 ·Status: COMPLETED ·Phase: PHASE2
-
Trial of Simvastatin in Amnestic Mild Cognitive Impairment (MCI) Patients
NCT00842920 ·Status: UNKNOWN ·Phase: PHASE4
-
Evaluation of the Efficacy and Safety of Azeliragon (TTP488) in Patients With Mild Alzheimer's Disease
NCT02080364 ·Status: TERMINATED ·Phase: PHASE3
-
4 Week, Safety and Tolerability Study in Patients With Mild to Moderate Alzheimer's Disease
NCT01039701 ·Status: COMPLETED ·Phase: PHASE2
-
An Efficacy and Safety Study of Atabecestat in Participants Who Are Asymptomatic at Risk for Developing Alzheimer's Dementia
NCT02569398 ·Status: TERMINATED ·Phase: PHASE2/PHASE3
-
Evaluating Simvastatin's Potential Role in Therapy
NCT00486044 ·Status: COMPLETED ·Phase: PHASE2
-
The Safety and Efficacy of an Investigational Drug in Delaying the Progression of Alzheimer's Disease
NCT00006187 ·Status: TERMINATED ·Phase: PHASE3
-
Clinical Trial to Determine Tolerable Dosis of Vorinostat in Patients With Mild Alzheimer Disease
NCT03056495 ·Status: TERMINATED ·Phase: PHASE1