Lipitor as a Treatment for Alzheimer's Disease
NCT00024531 · Status: COMPLETED · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 98
Last updated 2006-11-09
Summary
The purpose of this study is to assess the clinical benefit of Lipitor, a cholesterol-lowering drug, in the treatment of Alzheimer's disease.
Conditions
- Alzheimer Disease
Interventions
- DRUG
-
Atorvastatin calcium
Sponsors & Collaborators
- collaborator INDUSTRY
-
Institute for the Study of Aging (ISOA)
lead OTHER
Principal Investigators
-
David L Sparks, PhD · Sun Health Research Institute
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- DOUBLE
Eligibility
- Min Age
- 50 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2000-10-31
- Completion
- 2004-08-31
Countries
- United States
Study Locations
More Related Trials
-
A Safety and Tolerability Evaluation of Two 10-Week Dose Regimens of Orally-Administered PF-04494700 in Alzheimer's Patients
NCT00141661 ·Status: COMPLETED ·Phase: PHASE2
-
The Safety and Efficacy of an Investigational Drug in Delaying the Progression of Alzheimer's Disease
NCT00006187 ·Status: TERMINATED ·Phase: PHASE3
-
Tolerability and Safety of Subcutaneous Administration of Affitope AD01 in Mild to Moderate Alzheimer's Disease
NCT00495417 ·Status: COMPLETED ·Phase: PHASE1
-
The Effect of Short-Term Statins and NSAIDs on Levels of Beta-Amyloid, a Protein Associated With Alzheimer's Disease
NCT00046358 ·Status: COMPLETED ·Phase: PHASE4
-
Trial of Simvastatin in Amnestic Mild Cognitive Impairment (MCI) Patients
NCT00842920 ·Status: UNKNOWN ·Phase: PHASE4
-
Safety and Efficacy Study of ALZT-OP1 in Subjects With Evidence of Early Alzheimer's Disease
NCT02547818 ·Status: COMPLETED ·Phase: PHASE3
-
Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of ABT-957 in Subjects With Mild-to-Moderate Alzheimer's Disease on Stable Doses of Acetylcholinesterase Inhibitors
NCT02220738 ·Status: TERMINATED ·Phase: PHASE1
-
A Trial of SHR-1707 Infusion in Patients With Mild Cognitive Impairment Due to Alzheimer's Disease and Mild Alzheimer's Disease
NCT06114745 ·Status: COMPLETED ·Phase: PHASE1
-
Discontinuation of Cholinesterase Inhibitors for the Treatment of Severe Alzheimer's Disease
NCT02035982 ·Status: COMPLETED ·Phase: PHASE3
-
Safety and Efficacy of TRx0237 in Subjects With Alzheimer's Disease Followed by Open-Label Treatment
NCT03446001 ·Status: COMPLETED ·Phase: PHASE3
-
Efficacy, Safety, & Tolerability of AZD3480 Patients With Mild to Moderate Dementia of the Alzheimer's Type (AD)
NCT01466088 ·Status: COMPLETED ·Phase: PHASE2
-
Study Evaluating SRA-333 in Mild to Moderate Alzheimer's Disease (AD)
NCT00151333 ·Status: COMPLETED ·Phase: PHASE2
-
A Study of LY3303560 in Participants With Early Symptomatic Alzheimer's Disease
NCT03518073 ·Status: COMPLETED ·Phase: PHASE2
-
Randomized I/II Phase Study of ALZT-OP1 Combination Therapy in Alzheimer's Disease and Normal Healthy Volunteers
NCT04570644 ·Status: COMPLETED ·Phase: PHASE1
-
Tolerability and Safety of Subcutaneous Administration of AFFITOPE AD02 in Mild to Moderate Alzheimer's Disease
NCT00633841 ·Status: COMPLETED ·Phase: PHASE1
-
An Efficacy and Safety Study of Atabecestat in Participants Who Are Asymptomatic at Risk for Developing Alzheimer's Dementia
NCT02569398 ·Status: TERMINATED ·Phase: PHASE2/PHASE3
-
Effect of LY450139 on the Long Term Progression of Alzheimer's Disease
NCT00594568 ·Status: COMPLETED ·Phase: PHASE3
-
A Clinical Study to Assess Single and Repeat Doses of a New Medication (GSK933776) in Patients With Alzheimer's Disease
NCT00459550 ·Status: COMPLETED ·Phase: PHASE1
-
PTI-125 for Mild-to-moderate Alzheimer's Disease Patients
NCT03748706 ·Status: COMPLETED ·Phase: PHASE2
-
Motor Slowing and Its Lesion-related Correlates in Alzheimer's Disease
NCT02811653 ·Status: UNKNOWN ·Phase: NA
-
Study With Lu AF87908 in Healthy Participants and Participants With Alzheimer's Disease
NCT04149860 ·Status: COMPLETED ·Phase: PHASE1
-
A Phase 1 Study of the Safety, Tolerability and Pharmacokinetics of ABT-126 in Subjects With Alzheimer's Disease
NCT01482845 ·Status: COMPLETED ·Phase: PHASE1
-
Statins, Cholesterol and Cognitive Decline in Alzheimer's
NCT06635252 ·Status: COMPLETED
-
Safety, Tolerability and the Effects on Cerebrospinal Fluid Spectrin Breakdown Product-145 Levels of ABT-957 in Subjects With Mild Alzheimer's Disease and Mild Cognitive Impairment
NCT02573740 ·Status: TERMINATED ·Phase: PHASE1
-
Statin Effects on Beta-Amyloid and Cerebral Perfusion in Adults at Risk for Alzheimer's Disease
NCT00939822 ·Status: COMPLETED ·Phase: PHASE2