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Opioid Agonist and Antagonist Effects on Opioid Dependence

NCT00142727 · Status: TERMINATED · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 16

Last updated 2017-01-12

No results posted yet for this study

Summary

The purpose of this study is to examine the acute agonist and antagonist effects of a full opioid agonist medication, an opioid antagonist medication, and a partial opioid agonist medication in individuals who have different levels of physical opioid dependence.

Conditions

  • Opioid-Related Disorders

Interventions

DRUG

Methadone

DRUG

Full opioid agonist

DRUG

Partial opioid agonist

DRUG

Opioid antagonist

Sponsors & Collaborators

Principal Investigators

  • Eric C. Strain, MD · Johns Hopkins University

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
55 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2004-01-31
Completion
2006-02-28

Countries

  • United States

Study Locations

More Related Trials

Entities

Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00142727 on ClinicalTrials.gov