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Molecular and Immunological Tools for Detection of Strain Diversity, Drug Resistance and Immunological Responses

NCT00138437 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 1554

Last updated 2014-11-07

No results posted yet for this study

Summary

The purpose of this study is to determine what factors contribute to the continued incidence of leprosy in Colombia. Study participants will include volunteering and consenting individuals, older than 4 years of age, representing three study groups:

1. healthy persons with no known contact with leprosy patients
2. patients reporting at Instituto Colombiano de Medicina Tropical-CES and Impresa Social del Estado Sanatorio Agua de Dios with a new diagnosis of leprosy or relapse of leprosy
3. household contacts of leprosy patients described in group 2. Blood, nasal swabs, slit skin smears, and biopsies will be taken from the volunteers to learn the strains of leprosy-causing bacteria in the area, the immune responses (body's response to disease) in local residents against the bacteria, and the pattern of leprosy transmission. Individuals will participate in this study for 1-10 days, and the study will last for 3 years.

Conditions

  • Leprosy

Sponsors & Collaborators

  • National Institute of Allergy and Infectious Diseases (NIAID)

    collaborator NIH

  • Colorado State University

    lead OTHER

Principal Investigators

  • Varalakshmi Vissa, PhD · Colorado State University

  • Nora Cardona-Castro, MD, MSc · Instituto Colombiano de Medicina Tropical - Universidad CES

Eligibility

Min Age
18 Years
Max Age
70 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2006-04-30
Primary Completion
2013-04-30
Completion
2013-04-30

Countries

  • Colombia

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00138437 on ClinicalTrials.gov