Paclitaxel, Carboplatin and Gemcitabine in the Treatment of Patients With Advanced Transitional Cell Cancer of the Bladder
NCT00136175 · Status: COMPLETED · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 68
Last updated 2015-01-21
Summary
This trial will evaluate the efficacy and safety of combination chemotherapy (paclitaxel, carboplatin, and gemcitabine) prior to surgery in the treatment of patients with locally advanced transitional cell cancer of the bladder.
Conditions
Interventions
- DRUG
- DRUG
- DRUG
Sponsors & Collaborators
-
University of Michigan Rogel Cancer Center
lead OTHER
Principal Investigators
-
David C. Smith, MD · The University of Michigan Comprehensive Cancer Center
Study Design
- Allocation
- NON_RANDOMIZED
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 1999-11-30
- Primary Completion
- 2005-12-31
- Completion
- 2007-10-31
Countries
- United States
Study Locations
More Related Trials
-
Gemcitabine and Carboplatin After Progression on Enfortumab Vedotin and Pembrolizumab in Advanced/Metastatic Urothelial Carcinoma
NCT07043972 ·Status: RECRUITING ·Phase: PHASE2
-
Paclitaxel and Carboplatin in Treating Patients With Locally Advanced or Metastatic Renal Cell Cancer
NCT00077129 ·Status: COMPLETED ·Phase: PHASE2
-
Capecitabine, Carboplatin and Weekly Paclitaxel for Patients With Solid Tumors and Adenocarcinoma of Unknown Primary
NCT00201734 ·Status: TERMINATED ·Phase: PHASE1/PHASE2
-
Combination Chemotherapy in Treating Patients With Transitional Cell Cancer of the Urothelium
NCT00014274 ·Status: COMPLETED ·Phase: PHASE2/PHASE3
-
S0028, Gemcitabine and Paclitaxel in Treating Patients With Advanced or Recurrent Cancer of the Urinary Tract
NCT00022633 ·Status: TERMINATED ·Phase: PHASE2
-
Oxaliplatin With Gemcitabine in Patients With Carcinoma of the Urothelial Tract
NCT00127595 ·Status: TERMINATED ·Phase: PHASE2
-
Cisplatin, Paclitaxel, and Gemcitabine in Treating Patients With Progressive Unresectable Regional or Metastatic Bladder Cancer
NCT00006118 ·Status: UNKNOWN ·Phase: PHASE2
-
Cisplatin Plus Gemcitabine With or Without Paclitaxel in Treating Patients With Stage IV Urinary Tract Cancer
NCT00022191 ·Status: COMPLETED ·Phase: PHASE3
-
Trastuzumab (Herceptin), Paclitaxel, Carboplatin and Gemcitabine in Advanced Urothelial Cancer
NCT00151034 ·Status: COMPLETED ·Phase: PHASE2
-
S0121, Neoadjuvant Carboplatin, Paclitaxel, and Gemcitabine Followed by Cisplatin and Radiation Therapy in Treating Patients With Locally Advanced or Recurrent Carcinoma of the Urothelium
NCT00055835 ·Status: COMPLETED ·Phase: PHASE2
-
Combination Chemotherapy in Treating Patients With Advanced Cancer of the Urothelium and Decreased Kidney Function
NCT00005644 ·Status: COMPLETED ·Phase: PHASE2
-
Combination Chemotherapy in Treating Patients With Stage IV Locally Advanced or Metastatic Bladder Cancer
NCT00005086 ·Status: COMPLETED ·Phase: PHASE2
-
Carboplatin and Gemcitabine in Treating Patients With Advanced Solid Tumors
NCT00021346 ·Status: COMPLETED ·Phase: PHASE1
-
Gemcitabine and Cisplatin Without Cystectomy for Patients With Muscle Invasive Bladder Urothelial Cancer and Select Genetic Alterations
NCT03609216 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
Gemcitabine Hydrochloride and Cisplatin or High-Dose Methotrexate, Vinblastine, Doxorubicin Hydrochloride, and Cisplatin in Treating Patients With Urothelial Cancer
NCT01639521 ·Status: WITHDRAWN ·Phase: PHASE2
-
Gemcitabine, Paclitaxel, and Cisplatin in Treating Patients With Advanced Cancer of the Urothelium
NCT00310011 ·Status: COMPLETED ·Phase: PHASE2
-
Combination Chemotherapy Following Surgery in Treating Patients With Urinary Tract Cancer
NCT00028860 ·Status: COMPLETED ·Phase: PHASE2
-
Phase II Trial of Gemcitabine, Carboplatin, and Bevacizumab in Chemotherapy Naive Patients With Advanced/Metastatic Urothelial Carcinoma
NCT00588666 ·Status: COMPLETED ·Phase: PHASE2
-
Carboplatin, Paclitaxel, and Everolimus in Treating Patients With Previously Untreated Cancer of Unknown Primary
NCT00936702 ·Status: COMPLETED ·Phase: PHASE2
-
Paclitaxel Albumin-Stabilized Nanoparticle Formulation After Cisplatin-Based Chemotherapy and Surgery in Treating Patients With High-Risk Bladder Cancer
NCT02718742 ·Status: WITHDRAWN ·Phase: PHASE2
-
Gemcitabine in Treating Patients With Recurrent or Refractory Bladder Cancer
NCT00014287 ·Status: WITHDRAWN ·Phase: PHASE1
-
Phase 2 Trial of Nab-paclitaxel Plus S-1 vs Gemcitabine Plus Cisplatin as 1-line Chemotherapy of Patients With Local Advanced and/or Metastatic Transitional Cell Carcinoma of Urothelial Tract
NCT03051373 ·Status: COMPLETED ·Phase: PHASE2
-
Gemcitabine Hydrochloride and Cisplatin Before Surgery in Treating Patients With Muscle Invasive Bladder Cancer
NCT01611662 ·Status: TERMINATED ·Phase: PHASE2
-
Palbociclib With Cisplatin or Carboplatin in Advanced Solid Tumors
NCT02897375 ·Status: COMPLETED ·Phase: PHASE1
-
Chemotherapy Before Surgery in Treating Patients With High Grade Upper Urinary Tract Cancer
NCT02412670 ·Status: COMPLETED ·Phase: PHASE2