Bioavailability and Effectiveness of Transdermally Administered Morphine
NCT00125684 · Status: COMPLETED · Phase: PHASE1 · Type: INTERVENTIONAL · Enrollment: 6
Last updated 2012-01-19
Summary
Patients will participate in two arms of the trial, one in which morphine will be administered transdermally, and, after a 3 day wash out period, one in which morphine will be administered subcutaneously.
Conditions
Interventions
- DRUG
-
morphine
Sponsors & Collaborators
-
Tom Baker Cancer Centre
collaborator OTHER -
Alberta Health services
lead OTHER
Principal Investigators
-
Neil Hagen · Alberta Cancerboard
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- PARALLEL
Eligibility
- Min Age
- 18 Years
- Max Age
- 65 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2003-07-31
- Primary Completion
- 2007-07-31
- Completion
- 2008-07-31
Countries
- Canada
Study Locations
More Related Trials
-
Analgesic Tolerance to Repeated Doses of Subcutaneous Morphine
NCT00256347 ·Status: COMPLETED ·Phase: NA
-
A Relative Bioavailability Study of Fentanyl 25 μg/h Transdermal System
NCT00864565 ·Status: COMPLETED ·Phase: PHASE1
-
Pharmacokinetic Evaluation of Nalmefene Administered Intranasally to Healthy Volunteers
NCT03129347 ·Status: COMPLETED ·Phase: PHASE1
-
Phase II Clinical Trial of Fentanyl Transdermal Matrix Patch, in the Management of Cancer Pain- Assessment of Effectiveness, Safety and Pharmacokinetics -
NCT00216658 ·Status: COMPLETED ·Phase: PHASE2
-
Morphine Versus Methadone As First Line Strong Opioid for Cancer Pain
NCT00634010 ·Status: TERMINATED ·Phase: PHASE3
-
Analgesic Treatment for Cancer Pain in South East Asia
NCT02664987 ·Status: COMPLETED
-
A Safety and Efficacy Study of Sufentanil Transdermal System in Patients With Chronic Pain Due to Cancer
NCT00943566 ·Status: WITHDRAWN ·Phase: PHASE2
-
A Efficacy and Safety Trial of Controlled Release (CR) Morphine in Cancer Patients
NCT00446069 ·Status: COMPLETED ·Phase: PHASE2
-
Sublingual Methadone for the Management of Cancer-related Procedure Pain in Inpatients
NCT00351637 ·Status: TERMINATED ·Phase: PHASE2
-
Comparison of A Single Dose Combination of Methadone and Morphine With Morphine Alone for Treating Post-operative Pain
NCT00142519 ·Status: COMPLETED ·Phase: PHASE2
-
Effectiveness and Tolerance of Inhaled Fentanyl Aerosol (25µg/Dose) in Chinese Patients With Breakthrough Cancer Pain
NCT04713189 ·Status: UNKNOWN ·Phase: PHASE1/PHASE2
-
Correlation Between the Analgesic Effect of Fentanyl Transdermal Patches and Nutritional Status in Cancer Pain Patients
NCT06369961 ·Status: COMPLETED
-
Acetaminophen for Cancer Pain
NCT00152854 ·Status: COMPLETED ·Phase: PHASE3
-
Opioid Titration Order Sheet or Standard Care in Treating Patients With Cancer Pain
NCT00666211 ·Status: COMPLETED ·Phase: PHASE3
-
Treatment for Chronic Pain in Patients With Advanced Cancer
NCT00003687 ·Status: COMPLETED ·Phase: PHASE3
-
Efficacy and Safety of Ultra-low Dose Methadone as Adjuvant Analgesic in Cancer Patients With Pain
NCT02687347 ·Status: UNKNOWN ·Phase: PHASE3
-
Role of Methadone As Co-Opioid Analgesic
NCT00558870 ·Status: TERMINATED ·Phase: PHASE2
-
Cannabis Oil for Pain Effectiveness
NCT03522467 ·Status: UNKNOWN ·Phase: PHASE2
-
Cordotomy in Reducing Pain in Patients With Advanced Cancer
NCT04119037 ·Status: ACTIVE_NOT_RECRUITING ·Phase: NA
-
Pharmacokinetics of Naltrexone Following Intravenous and Oral Routes of Administration in Healthy Volunteers
NCT00714584 ·Status: COMPLETED ·Phase: PHASE1
-
Switching From Morphine to Methadone. A Clinical, Pharmacological and Pharmacogenetic Study
NCT00184496 ·Status: COMPLETED ·Phase: PHASE3
-
Evaluation of Efficacy and Safety of Subcutaneous Acetaminophen
NCT03635684 ·Status: COMPLETED ·Phase: PHASE2
-
Prospective Evaluation of Intrathecal Targeted Drug Delivery for Cancer Associated Pain
NCT05674240 ·Status: COMPLETED
-
Real World Study of Oxycodone Sustained-release Tablets for Patients With Moderate to Severe Cancer Pain
NCT05962294 ·Status: UNKNOWN
-
Opioid Titration With 12.5 ug/h Fentanyl Transdermal Patch vs Orally Morphine for Opioid-naïve Patients With Moderate Cancer Pain
NCT04533243 ·Status: UNKNOWN ·Phase: PHASE3