The Effect of Fasudil on Vascular Function in Humans
NCT00120718 · Status: COMPLETED · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 60
Last updated 2008-09-30
Summary
The purpose of the study is to evaluate how the rho kinase inhibitor, fasudil, affects vascular function in patients with atherosclerosis and hyperlipidemia.
Conditions
Interventions
- DRUG
-
fasudil
Sponsors & Collaborators
-
Brigham and Women's Hospital
lead OTHER
Principal Investigators
-
Mark A Creager, MD · Brigham and Women's Hospital
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- DOUBLE
- Model
- CROSSOVER
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2002-06-30
- Primary Completion
- 2007-01-31
- Completion
- 2007-01-31
Countries
- United States
Study Locations
More Related Trials
-
Rosuvastatin and Ischemia Reperfusion
NCT00315510 ·Status: COMPLETED ·Phase: PHASE2
-
48-wk Open Label Phase IIIb to Evaluate Efficacy and Safety
NCT00654602 ·Status: COMPLETED ·Phase: PHASE3
-
A Study to Estimate the Effect of AZD5718 on the Pharmacokinetics (What Does the Body Does to the Drug) of Rosuvastatin to Measure the Relative Bioavailability (the Extent to Which a Drug or Other Substance Becomes Available to the Body) of AZD5718 Oral Suspension vs AZD5718 Immediate Release Tablet
NCT02963116 ·Status: COMPLETED ·Phase: PHASE1
-
A Study To Evaluate the Effect of Rosuvastatin On Intravascular Ultrasound-Derived Coronary Atheroma Burden (ASTEROID)
NCT00240318 ·Status: COMPLETED ·Phase: PHASE3
-
A Study to Assess the Effect of RO4607381 in Patients With Relatively Low Levels of High Density Lipoprotein-Cholesterol (HDL-C)
NCT00697203 ·Status: COMPLETED ·Phase: PHASE2
-
Effect of Rosuvastatin Therapy on HDL2 Level
NCT02593487 ·Status: UNKNOWN ·Phase: PHASE4
-
A Study to Assess the Effect of AZD0780 on the Pharmacokinetics of Rosuvastatin.
NCT05787002 ·Status: COMPLETED ·Phase: PHASE1
-
A Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of HS-10510 in Healthy Subjects
NCT07001787 ·Status: NOT_YET_RECRUITING ·Phase: PHASE1
-
A Study in Healthy Men to Test the Influence of BI 1323495 on the Amount of the Medicines Rosuvastatin and Dabigatran in the Blood
NCT04257032 ·Status: COMPLETED ·Phase: PHASE1
-
Rosuvastatin in the Long-term Treatment of Hypercholesterolaemic Subjects With Coronary Heart Disease
NCT00329160 ·Status: COMPLETED ·Phase: PHASE4
-
Comparison of the Bioavailability of Fenofibric Acid and Rosuvastatin From ABT-143 Relative to That From the Coadministration of ABT-335 (Fenofibric Acid) and Rosuvastatin Calcium
NCT00808678 ·Status: COMPLETED ·Phase: PHASE1
-
Effect of rHDL on Atherosclerosis - Safety and Efficacy: THE ERASE TRIAL
NCT00225719 ·Status: COMPLETED ·Phase: PHASE2
-
Multicenter, Prospective, Randomized, Controlled, Double-blind Trial on the Impact of Rosuvastatin on Subclinical Markers of Atherosclerosis in Patients With Primary Necrotizing Vasculitides
NCT02117453 ·Status: COMPLETED ·Phase: PHASE3
-
LDL-C Lowering Efficacy and Safety of Rosuvastatin 20 mg/Day to10 mg/Day in Chinese ACS(Acute Coronary Syndrome) Patients
NCT02077257 ·Status: UNKNOWN ·Phase: PHASE4
-
To Explore the Treatment Effect of Various Commercially Available Statins on Patients With Hyperlipidemia
NCT00726362 ·Status: COMPLETED
-
A Clinical Trial to Evaluate the Pharmacokinetics and Safety of Fimasartan and Rosuvastatin in Healthy Male Subjects
NCT02704702 ·Status: COMPLETED ·Phase: PHASE1
-
Pharmacokinetic Drug Interaction Between Rosuvastatin and Valsartan
NCT01609907 ·Status: COMPLETED ·Phase: PHASE1
-
Drug Interaction Study With Rosuvastatin
NCT02101125 ·Status: COMPLETED ·Phase: PHASE1
-
Drug Interaction Statin
NCT02089061 ·Status: COMPLETED ·Phase: PHASE1
-
The Effect of Rosuvastatin on Adenosine Metabolism
NCT00554138 ·Status: COMPLETED ·Phase: NA
-
Polygenic Risk-based Detection of Subclinical Coronary Atherosclerosis and Intervention With Statin and Colchicine
NCT05850091 ·Status: RECRUITING ·Phase: PHASE4
-
Resuvastatin Treatment for Symptomatic Middle Cerebral Artery Stenosis Based on High-resolution Magnetic Resonance Imaging
NCT02041117 ·Status: COMPLETED ·Phase: PHASE4
-
Progression of Carotid Artery Atheroma in Moderately Hypercholesterolemic Subjects
NCT00654394 ·Status: COMPLETED ·Phase: PHASE3
-
A Pharmacokinetic Interaction Study Between JNJ-54861911 and Transporter Substrates Rosuvastatin and Metformin in Healthy Participants
NCT02611518 ·Status: COMPLETED ·Phase: PHASE1
-
Rosuvastatin Effect on Reducing Coronary Atherosclerosis Plaques Volume
NCT01382277 ·Status: UNKNOWN ·Phase: PHASE4