Use of Topotecan in Patients With Refractory Acute Leukemia
NCT00100477 · Status: COMPLETED · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 10
Last updated 2013-09-25
Summary
The purpose of this study is to identify the highest tolerated doses in drugs used to treat aggressive leukemia, lymphoma or multiple myeloma not responding to standard chemotherapy treatment. The drugs being used in this study include drugs frequently used in treating such diseases (mitoxantrone and etoposide) as well as a newer drug that has also been shown to be effective (topotecan).
Conditions
- Non-Hodgkin's Lymphoma
- Leukemia
Interventions
- DRUG
-
Topotecan
- DRUG
-
Mitozantrone
- DRUG
-
Etoposide
Sponsors & Collaborators
-
Immunex Corporation
collaborator INDUSTRY -
SmithKline Beecham
collaborator INDUSTRY - collaborator INDUSTRY
-
US Department of Veterans Affairs
lead FED
Principal Investigators
-
Mark Mainwaring · North Florida/South Georgia Veterans Health System
Eligibility
- Min Age
- 18 Years
- Max Age
- 60 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 1998-08-31
- Primary Completion
- 2001-01-31
- Completion
- 2001-06-30
Countries
- United States
Study Locations
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