Non-small Cell Lung Cancer Study US75 (Z-PACT)
NCT00086268 · Status: COMPLETED · Phase: PHASE3 · Type: INTERVENTIONAL · Enrollment: 250
Last updated 2017-09-13
Summary
This study will evaluate the effects of an investigational drug in combination with chemotherapy in patients with stage IIIB/IV non-small cell lung cancer. This study will measure the effects of this combination on progression of lung cancer, cancer response to treatments, and development of cancer-related bone lesions.
Conditions
- Non Small Cell Lung Carcinoma
Interventions
- DRUG
-
zoledronic acid
- DRUG
-
Taxotere
- DRUG
Sponsors & Collaborators
- lead INDUSTRY
Principal Investigators
-
Novartis Pharmaceuticals · Novartis Pharmaceuticals
Study Design
- Allocation
- RANDOMIZED
- Purpose
- PREVENTION
- Masking
- NONE
- Model
- PARALLEL
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2004-04-30
- Primary Completion
- 2007-10-31
- Completion
- 2007-10-31
Countries
- United States
Study Locations
More Related Trials
-
Non-small Cell Lung Cancer Registry
NCT00099541 ·Status: COMPLETED ·Phase: PHASE4
-
Safety and Efficacy Study of Nab®-Paclitaxel With CC-486 or Nab®-Paclitaxel With Durvalumab, and Nab®-Paclitaxel Monotherapy as Second/Third-line Treatment for Advanced Non-small Cell Lung Cancer
NCT02250326 ·Status: COMPLETED ·Phase: PHASE2
-
Combination Chemotherapy Plus Peripheral Stem Cell Transplantation in Treating Patients With Small Cell Lung Cancer
NCT00003860 ·Status: COMPLETED ·Phase: PHASE2
-
Induction Chemotherapy Using Paclitaxel, Carboplatin, CPT-11 With Pegfilgrastim
NCT00280787 ·Status: COMPLETED ·Phase: PHASE2
-
Study of Pazopanib and Paclitaxel in Advanced Non-small Cell Lung Cancer
NCT00866528 ·Status: COMPLETED ·Phase: PHASE1
-
Testing of Tazemetostat in Combination With Topotecan and Pembrolizumab in Patients With Recurrent Small Cell Lung Cancer
NCT05353439 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE1
-
Suramin, Paclitaxel, and Carboplatin in Treating Patients With Stage IIIB or Stage IV Non-small Cell Lung Cancer
NCT00006929 ·Status: COMPLETED ·Phase: PHASE2
-
Combination Chemotherapy in Treating Patients With Extensive-Stage Small Cell Lung Cancer
NCT00025272 ·Status: COMPLETED ·Phase: PHASE2
-
Neoadjuvant MPDL3280A, Nab-paclitaxel and Carboplatin (MAC) in NSCLC
NCT02716038 ·Status: COMPLETED ·Phase: PHASE2
-
Study of Abraxane and Carboplatin to Treat Small Cell Lung Cancer
NCT00454324 ·Status: TERMINATED ·Phase: PHASE2
-
Topotecan and Paclitaxel in Treating Patients With Recurrent or Refractory Small Cell Lung Cancer
NCT00003281 ·Status: COMPLETED ·Phase: PHASE2
-
CS-1008 With Carboplatin/Paclitaxel in Chemotherapy naïve Subjects With Metastatic or Unresectable Non-small Cell Lung Cancer (NSCLC)
NCT00991796 ·Status: COMPLETED ·Phase: PHASE2
-
Topotecan Hydrochloride and Doxorubicin Hydrochloride in Treating Relapsed or Refractory Small Cell Lung Cancer
NCT00856037 ·Status: COMPLETED ·Phase: PHASE1
-
Paclitaxel Albumin-Stabilized Nanoparticle Formulation and Carboplatin in Treating Patients With Stage IIIB, Stage IV, or Recurrent Non-Small Cell Lung Cancer
NCT00729612 ·Status: COMPLETED ·Phase: PHASE2
-
A Study for Small Cell Lung Cancer (SCLC) in Extensive Disease Stage
NCT00168896 ·Status: UNKNOWN ·Phase: PHASE2/PHASE3
-
Bortezomib Plus Gemcitabine and Carboplatin in Treating Patients With Advanced or Recurrent Non-Small Cell Lung Cancer
NCT00052338 ·Status: COMPLETED ·Phase: PHASE1
-
AZD1775 Plus Carboplatin-Paclitaxel in Squamous Cell Lung Cancer
NCT02513563 ·Status: COMPLETED ·Phase: PHASE2
-
Topotecan and Carboplatin in the First-Line Treatment of Patients With Extensive Stage Small Cell Lung Cancer
NCT00305942 ·Status: COMPLETED ·Phase: PHASE2
-
S9914: Combination Chemotherapy Plus Filgrastim in Untreated Extensive-Stage Small Cell Lung Cancer
NCT00004137 ·Status: COMPLETED ·Phase: PHASE2
-
Study of Olaparib and Temozolomide in Patients With Recurrent Small Cell Lung Cancer Following Failure of Prior Chemotherapy
NCT02446704 ·Status: UNKNOWN ·Phase: PHASE1/PHASE2
-
S9806: Combination Chemotherapy in Treating Patients With Stage IIIB or Stage IV Non-small Cell Lung Cancer
NCT00003587 ·Status: COMPLETED ·Phase: PHASE2
-
Combination Chemotherapy in Treating Patients With Stage IIIB, Stage IV, or Recurrent Non-Small Cell Lung Cancer
NCT00054392 ·Status: WITHDRAWN ·Phase: PHASE3
-
R-(-)-Gossypol Acetic Acid in Treating Patients With Recurrent Extensive-Stage Small Cell Lung Cancer
NCT00773955 ·Status: COMPLETED ·Phase: PHASE2
-
ZD6474 Alone or in Combination With Paclitaxel and Carboplatin in Subjects With Previously Untreated Locally Advanced or Metastatic Non-small Cell Lung Cancer (NSCLC)
NCT00071188 ·Status: COMPLETED ·Phase: PHASE2
-
Combination Chemotherapy in Treating Patients With Advanced Non-Small Cell Lung Cancer
NCT00005806 ·Status: COMPLETED ·Phase: PHASE1