Genetic Analysis in Identifying Late-Occurring Complications in Childhood Cancer Survivors
NCT00082745 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 3885
Last updated 2026-05-18
Summary
This clinical trial studies cancer survivors to identify those who are at increased risk of developing late-occurring complications after undergoing treatment for childhood cancer. A patient's genes may affect the risk of developing complications, such as congestive heart failure, avascular necrosis, stroke, and second cancer, years after undergoing cancer treatment. Genetic studies may help doctors identify survivors of childhood cancer who are more likely to develop late complications.
Conditions
- Childhood Malignant Neoplasm
Interventions
- OTHER
-
Laboratory Biomarker Analysis
Correlative studies
- OTHER
-
Questionnaire Administration
Ancillary studies
Sponsors & Collaborators
-
National Cancer Institute (NCI)
collaborator NIH -
Children's Oncology Group
lead NETWORK
Principal Investigators
-
Smita Bhatia · Children's Oncology Group
Eligibility
- Max Age
- 99 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2004-03-25
- Primary Completion
- 2004-12-31
- Completion
- 2026-03-31
Countries
- United States
- Australia
- Canada
- Puerto Rico
- Switzerland
Study Locations
More Related Trials
-
Diagnostic Study of Gene Alterations in Children Who Have Been Treated for Relapsed Acute Lymphocytic Leukemia
NCT00003933 ·Status: COMPLETED ·Phase: NA
-
Collecting and Storing Samples of Bone Marrow and Blood From Patients With Relapsed Acute Lymphoblastic Leukemia or Non-Hodgkin Lymphoma
NCT00897325 ·Status: COMPLETED
-
A Longitudinal Assessment of Frailty in Young Adult Survivors of Childhood Cancer
NCT02256137 ·Status: ACTIVE_NOT_RECRUITING
-
Combination Chemotherapy in Treating Children With Acute Lymphocytic Leukemia
NCT00002812 ·Status: COMPLETED ·Phase: PHASE3
-
Combination Chemotherapy With or Without Peripheral Stem Cell Transplant in Treating Children With Acute Lymphoblastic Leukemia
NCT00022737 ·Status: COMPLETED ·Phase: PHASE3
-
Docetaxel in Treating Children With Relapsed or Refractory Acute Lymphoblastic or Acute Myeloid Leukemia
NCT00021242 ·Status: COMPLETED ·Phase: PHASE2
-
Approaches to Identify Early Biomarkers and Pathogenesis of Anthracycline Cardiotoxicity
NCT04036045 ·Status: WITHDRAWN
-
Combination Chemotherapy Followed By Peripheral Stem Cell Transplant in Treating Young Patients With Newly Diagnosed Supratentorial Primitive Neuroectodermal Tumors or High-Risk Medulloblastoma
NCT00336024 ·Status: COMPLETED ·Phase: PHASE3
-
Dietary and Exercise Interventions in Preventing Cardiovascular Disease in Younger Survivors of Leukemia, Lymphoma, or Brain Tumors
NCT02000986 ·Status: WITHDRAWN ·Phase: NA
-
Combination Chemotherapy in Treating Children With Lymphoma
NCT00002590 ·Status: COMPLETED ·Phase: PHASE2
-
Gemcitabine in Treating Children With Relapsed or Refractory Acute Lymphoblastic Leukemia or Acute Myelogenous Leukemia
NCT00006462 ·Status: COMPLETED ·Phase: PHASE2
-
Combination Chemotherapy in Treating Children With Newly Diagnosed Acute Lymphoblastic Leukemia
NCT00002744 ·Status: COMPLETED ·Phase: PHASE3
-
Combination Chemotherapy in Treating Young Patients With Recurrent or Resistant Malignant Germ Cell Tumors
NCT00467051 ·Status: COMPLETED ·Phase: PHASE2
-
Late Effects of Treatment for Sarcomas in Children
NCT00006515 ·Status: COMPLETED
-
Development of Strategies to Increase Enrollment in Clinical Trials for Children With Cancer
NCT00002485 ·Status: COMPLETED
-
Identifying, Understanding, and Overcoming Barriers to the Use of Clinical Practice Guidelines in Pediatric Oncology
NCT02847130 ·Status: COMPLETED
-
Docetaxel in Treating Children With Recurrent Solid Tumors
NCT00002825 ·Status: COMPLETED ·Phase: PHASE2
-
Combination Chemotherapy in Treating Children With Acute Lymphoblastic Leukemia
NCT00005585 ·Status: COMPLETED ·Phase: PHASE3
-
Late Effects After Treatment in Patients With Previously Diagnosed High-Risk Neuroblastoma
NCT03057626 ·Status: ACTIVE_NOT_RECRUITING
-
Long-Term Effects of Treatment in Patients Previously Treated for Childhood Hodgkin's Lymphoma
NCT00091091 ·Status: COMPLETED
-
A Study of Revumenib in Combination With Chemotherapy for Patients Diagnosed With Relapsed or Refractory Leukemia
NCT05761171 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
Neurobehavioral Complications in Children Who Were Previously Treated With Steroids and Intrathecal Therapy for Acute Lymphoblastic Leukemia
NCT00085176 ·Status: COMPLETED
-
Temsirolimus, Irinotecan Hydrochloride, and Temozolomide in Treating Younger Patients With Relapsed or Refractory Solid Tumors
NCT01141244 ·Status: COMPLETED ·Phase: PHASE1
-
Ex Vivo Drug Sensitivity Testing and Mutation Profiling
NCT03860376 ·Status: COMPLETED
-
Evaluating the Side Effects and How Well Anticancer Drugs Work in Very Young Patients With Cancer
NCT00897871 ·Status: UNKNOWN