Voriconazole in Preventing Fungal Infections in Children With Neutropenia After Chemotherapy
NCT00066599 · Status: COMPLETED · Phase: PHASE2 · Type: INTERVENTIONAL
Last updated 2013-06-19
Summary
RATIONALE: Voriconazole may be effective in preventing systemic fungal infections following chemotherapy.
PURPOSE: Phase II trial to study the effectiveness of voriconazole in preventing systemic fungal infections in children who have neutropenia after receiving chemotherapy for leukemia, lymphoma, or aplastic anemia or in preparation for bone marrow or stem cell transplantation.
Conditions
- Kidney Cancer
- Leukemia
- Lymphoma
- Multiple Myeloma and Plasma Cell Neoplasm
- Myelodysplastic Syndromes
- Myelodysplastic/Myeloproliferative Neoplasms
- Neuroblastoma
- Neutropenia
- Sarcoma
Interventions
- DRUG
-
voriconazole
Sponsors & Collaborators
-
National Cancer Institute (NCI)
lead NIH
Principal Investigators
-
Thomas J. Walsh, MD · National Cancer Institute (NCI)
Study Design
- Purpose
- SUPPORTIVE_CARE
- Masking
- NONE
Eligibility
- Min Age
- 2 Years
- Max Age
- 11 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2003-06-30
- Completion
- 2004-06-30
Countries
- United States
Study Locations
More Related Trials
-
Study Of The Pharmacokinetics And Safety Of Voriconazole In Children 2 To 11 Years Old Who Are At High Risk For Systemic Fungal Infection
NCT00739934 ·Status: COMPLETED ·Phase: PHASE2
-
An Open Label, Non-Comparative, Multicenter, Phase III Trial of the Efficacy, Safety and Toleration of Voriconazole in the Primary or Secondary Treatment of Invasive Fungal Infections
NCT00001810 ·Status: COMPLETED ·Phase: PHASE3
-
Efficacy of Prophylactic Itraconazole in High-Dose Chemotherapy and Autologous Hematopoietic Stem Cell Transplantation
NCT00336531 ·Status: COMPLETED ·Phase: PHASE4
-
Antifungal Use in Oncohematological Neutropenic Patients
NCT00386802 ·Status: COMPLETED ·Phase: PHASE4
-
Emergency Use of Voriconazole in Patients With Life-Threatening Invasive Fungal Infections
NCT00015665 ·Status: COMPLETED ·Phase: PHASE3
-
Caspofungin Versus Fluconazole in Preventing Invasive Fungal Infections (IFI) in Patients Undergoing Chemotherapy for Acute Myeloid Leukemia
NCT01307579 ·Status: COMPLETED ·Phase: PHASE3
-
MT2013-37R: Voriconazole Monitoring in Pediatric Stem Cell Transplant Patients
NCT02227797 ·Status: COMPLETED ·Phase: PHASE1
-
Voriconazole and Caspofungin Acetate in Treating Invasive Fungal Infections in Patients With Weakened Immune Systems
NCT00238355 ·Status: TERMINATED ·Phase: PHASE2
-
A Study of Safety and Pharmacokinetics of Repeated Dose of Micafungin as Antifungal Prophylaxis in Children and Adolescents Who Undergo Hematopoietic Stem Cell Transplant
NCT00606268 ·Status: COMPLETED ·Phase: PHASE1
-
Safety and Pharmacokinetics of Intravenous and Oral Posaconazole in Immunocompromised Children (MK-5592-097)
NCT02452034 ·Status: COMPLETED ·Phase: PHASE1
-
Caspofungin Acetate in Treating Children With Fever and Neutropenia
NCT00020527 ·Status: COMPLETED ·Phase: NA
-
Ravuconazole in Preventing Fungal Infections in Patients Undergoing Allogeneic Stem Cell Transplantation
NCT00064311 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Voriconazole Compared With Itraconazole in Preventing Fungal Infections in Patients Undergoing Allogeneic Hematopoietic Stem Cell Transplantation
NCT00079222 ·Status: COMPLETED ·Phase: NA
-
Immediate vs. Deferred Empirical Antifungal Treatment With Voriconazole In Neutropenic Patients
NCT00150345 ·Status: COMPLETED ·Phase: PHASE3
-
A Pharmacokinetic Study of Pediatric Micafungin Prophylaxis
NCT02057289 ·Status: TERMINATED ·Phase: PHASE1
-
Posaconazole Versus Micafungin for Prophylaxis Against Invasive Fungal Infections During Neutropenia in Patients Undergoing Chemotherapy for Acute Myelogenous Leukemia, Acute Lymphocytic Leukemia or Myelodysplastic Syndrome
NCT01200355 ·Status: COMPLETED ·Phase: PHASE4
-
A Study Of The Safety, Tolerability And Effective Of Voriconazole For The Treatment Of Serious Candida Infection And Candida Infection Of The Throat In Pediatric Patients
NCT01092832 ·Status: TERMINATED ·Phase: PHASE3
-
Phase I Study of the Safety, Tolerance, and Pharmacokinetics of FK463 in Immunocompromised Children With Fever and Neutropenia
NCT00001790 ·Status: COMPLETED ·Phase: PHASE1
-
Voriconazole Versus Itraconazole In Primary Prophylaxis Of Invasive Fungal Infection (IFI) In Subjects With Allogeneic Hematopoietic Stem Cell Transplants (HSCT)
NCT00289991 ·Status: COMPLETED ·Phase: PHASE3
-
A Study To Evaluate The Safety Of Voriconazole As Treatment Of Invasive Aspergillosis (Fungal Infection) And Other Rare Molds In Children
NCT00836875 ·Status: TERMINATED ·Phase: PHASE3
-
Pharmacokinetics of Itraconazole in Pediatric Cancer Patients
NCT01409018 ·Status: COMPLETED ·Phase: PHASE1
-
Voriconazole Pharmacokinetics in Children With Gastrointestinal Graft Versus Host Disease
NCT00792246 ·Status: COMPLETED ·Phase: PHASE1
-
Beta Glucan Assay in Patients Receiving Voriconazole Prophylaxis
NCT00904995 ·Status: COMPLETED ·Phase: PHASE3
-
Isavuconazole in Preventing Invasive Fungal Infections in Adult Patients With Newly Diagnosed Acute Myeloid Leukemia or Myelodysplastic Syndrome and Neutropenia
NCT03019939 ·Status: COMPLETED ·Phase: PHASE2
-
Voriconazole vs. Amphotericin B in the Treatment of Invasive Aspergillosis
NCT00001646 ·Status: COMPLETED ·Phase: PHASE3