Ravuconazole in Preventing Fungal Infections in Patients Undergoing Allogeneic Stem Cell Transplantation
NCT00064311 · Status: COMPLETED · Phase: PHASE1/PHASE2 · Type: INTERVENTIONAL
Last updated 2012-03-08
Summary
RATIONALE: Antifungals such as ravuconazole may be effective in preventing fungal infections in patients undergoing chemotherapy and stem cell transplantation.
PURPOSE: Phase I/II trial to study the effectiveness of ravuconazole in preventing fungal infections in patients undergoing allogeneic stem cell transplantation.
Conditions
- Breast Cancer
- Chronic Myeloproliferative Disorders
- Gestational Trophoblastic Tumor
- Infection
- Leukemia
- Lymphoma
- Multiple Myeloma and Plasma Cell Neoplasm
- Myelodysplastic Syndromes
- Myelodysplastic/Myeloproliferative Neoplasms
- Neuroblastoma
- Ovarian Cancer
- Testicular Germ Cell Tumor
Interventions
- DRUG
-
ravuconazole
Sponsors & Collaborators
-
National Cancer Institute (NCI)
collaborator NIH -
National Institutes of Health Clinical Center (CC)
lead NIH
Principal Investigators
-
Thomas J. Walsh, MD · National Cancer Institute (NCI)
Study Design
- Purpose
- SUPPORTIVE_CARE
- Masking
- NONE
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2003-06-30
- Completion
- 2004-09-30
Countries
- United States
Study Locations
More Related Trials
-
Isavuconazole in Preventing Invasive Fungal Infections in Adult Patients With Newly Diagnosed Acute Myeloid Leukemia or Myelodysplastic Syndrome and Neutropenia
NCT03019939 ·Status: COMPLETED ·Phase: PHASE2
-
Posaconazole Versus Micafungin for Prophylaxis Against Invasive Fungal Infections During Neutropenia in Patients Undergoing Chemotherapy for Acute Myelogenous Leukemia, Acute Lymphocytic Leukemia or Myelodysplastic Syndrome
NCT01200355 ·Status: COMPLETED ·Phase: PHASE4
-
Comparing the Effectiveness of Fluconazole and a New Medicine (FK463) in Preventing Fungal Infections in Bone Marrow Transplant Patients
NCT00001937 ·Status: COMPLETED ·Phase: PHASE3
-
Voriconazole for Secondary Prophylaxis of Invasive Fungal Infections in Patients With Allogeneic Stem Cell Transplants
NCT00143312 ·Status: COMPLETED ·Phase: PHASE4
-
A Study to Compare Efficacy and Safety of Mycamine® and Itraconazole for Preventing Fungal Infections
NCT00794703 ·Status: COMPLETED ·Phase: PHASE3
-
Comparison of Fluconazole vs Voriconazole to Treat Fungal Infections for Blood and Marrow Transplants (BMT CTN 0101)
NCT00075803 ·Status: COMPLETED ·Phase: PHASE3
-
Micafungin Prevention Study for Invasive Fungal Disease in Pediatric & Adolescent Patients Undergoing Autologous Hematopoietic Stem Cell Transplantation
NCT01417169 ·Status: UNKNOWN ·Phase: PHASE2
-
Oral Posaconazole Three Times Per Day vs Weekly High Dose Amphotericin B Lipid Complex (ABLC)
NCT00750737 ·Status: COMPLETED ·Phase: PHASE3
-
Caspofungin Versus Fluconazole in Preventing Invasive Fungal Infections (IFI) in Patients Undergoing Chemotherapy for Acute Myeloid Leukemia
NCT01307579 ·Status: COMPLETED ·Phase: PHASE3
-
Voriconazole Compared With Itraconazole in Preventing Fungal Infections in Patients Undergoing Allogeneic Hematopoietic Stem Cell Transplantation
NCT00079222 ·Status: COMPLETED ·Phase: NA
-
Voriconazole in Preventing Fungal Infections in Children With Neutropenia After Chemotherapy
NCT00066599 ·Status: COMPLETED ·Phase: PHASE2
-
Prophylaxis Trial in High Risk Allogenic Stem Cell Transplant Recipients With Graft vs. Host Disease
NCT00034645 ·Status: COMPLETED ·Phase: PHASE3
-
Micafungin Prevention Study for Fungal Disease in Child Receiving Allogenic Hematopoietic Stem Cell Transplantation
NCT01135589 ·Status: UNKNOWN ·Phase: PHASE4
-
Efficacy of Itraconazole as Secondary Prophylaxis in Patients Undergoing Allogeneic Stem Cell Transplantation or Chemotherapy With Prior Invasive Fungal Infection
NCT01198236 ·Status: COMPLETED ·Phase: PHASE4
-
Itraconazole Compared With Fluconazole to Prevent Infections in Patients Undergoing Peripheral Stem Cell or Bone Marrow Transplantation
NCT00003883 ·Status: COMPLETED ·Phase: PHASE3
-
An Open Label, Non-Comparative, Multicenter, Phase III Trial of the Efficacy, Safety and Toleration of Voriconazole in the Primary or Secondary Treatment of Invasive Fungal Infections
NCT00001757 ·Status: COMPLETED ·Phase: PHASE3
-
Posaconazole vs Itraconazole in Preventing IFD Post-HSCT
NCT03631602 ·Status: UNKNOWN ·Phase: PHASE2/PHASE3
-
Study of Rezafungin Compared to Standard Antimicrobial Regimen for Prevention of Invasive Fungal Diseases in Adults Undergoing Allogeneic Blood and Marrow Transplantation
NCT04368559 ·Status: COMPLETED ·Phase: PHASE3
-
Micafungin Prophylaxis During 1st Induction Chemotherapy for De Novo Acute Leukemia
NCT02440178 ·Status: COMPLETED ·Phase: PHASE2
-
Caspofungin Acetate in Treating Aspergillosis in Patients With Hematologic Cancer or in Patients Who Have Undergone a Stem Cell Transplant
NCT00110045 ·Status: COMPLETED ·Phase: PHASE2
-
Voriconazole Versus Itraconazole In Primary Prophylaxis Of Invasive Fungal Infection (IFI) In Subjects With Allogeneic Hematopoietic Stem Cell Transplants (HSCT)
NCT00289991 ·Status: COMPLETED ·Phase: PHASE3
-
Voriconazole vs. Amphotericin B in the Treatment of Invasive Aspergillosis
NCT00001646 ·Status: COMPLETED ·Phase: PHASE3
-
Voriconazole and Caspofungin Acetate in Treating Invasive Fungal Infections in Patients With Weakened Immune Systems
NCT00238355 ·Status: TERMINATED ·Phase: PHASE2
-
Anidulafungin Versus Fluconazole for the Prevention of Fungal Infections in Liver Transplant Recipients
NCT00841971 ·Status: COMPLETED ·Phase: PHASE4
-
Long-term Versus Short-term Sequential Therapy (Intravenous Itraconazole Followed by Oral Solution) of Itraconazole as Primary Prophylaxis in Patients Undergoing Allogeneic Stem Cell Transplantation
NCT01160952 ·Status: UNKNOWN ·Phase: PHASE2