Megestrol in Treating Patients Who Are Undergoing Radiation Therapy for Lung Cancer
NCT00031785 · Status: COMPLETED · Phase: PHASE3 · Type: INTERVENTIONAL · Enrollment: 25
Last updated 2021-09-09
Summary
RATIONALE: Megestrol helps improve appetite. It is not yet known if megestrol is effective in limiting weight loss in patients who are undergoing radiation therapy.
PURPOSE: Randomized phase III trial to determine the effectiveness of megestrol in limiting weight loss in patients who are undergoing radiation therapy for lung cancer.
Conditions
- Anorexia
- Cachexia
- Lung Cancer
Interventions
- DRUG
-
megestrol acetate
- RADIATION
-
radiation therapy
Sponsors & Collaborators
-
National Cancer Institute (NCI)
collaborator NIH -
Wake Forest University Health Sciences
lead OTHER
Principal Investigators
-
Edward G. Shaw, MD · Wake Forest University Health Sciences
Study Design
- Purpose
- SUPPORTIVE_CARE
Eligibility
- Min Age
- 18 Years
- Max Age
- 120 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2000-09-01
- Primary Completion
- 2002-09-11
- Completion
- 2002-09-11
- FDA Drug
- Yes
Countries
- United States
Study Locations
More Related Trials
-
Study to Compare the Effects of Repeated Doses of an Investigational New Drug and a Placebo on Appetite in Advanced Cancer and Anorexia
NCT04803305 ·Status: COMPLETED ·Phase: PHASE1
-
Low Antioxidant Diet in Controlling Cachexia in Patients With Oropharyngeal Cancer Receiving Chemotherapy and Radiation Therapy
NCT00486304 ·Status: COMPLETED ·Phase: PHASE1
-
A Study of Cancer Related Fatigue in Patients With Metastatic Cancer Receiving Anti-PD1 Immunotherapy
NCT03525873 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE3
-
Radiation Therapy Plus Topotecan in Treating Patients With Non-small Cell Lung Cancer
NCT00002537 ·Status: COMPLETED ·Phase: PHASE1
-
The Addition of Metformin to Definitive Radiotherapy in Patients With Stage III NSCLC
NCT04170959 ·Status: TERMINATED ·Phase: PHASE2
-
Time-Restricted Eating Versus Nutritional Counseling for the Reduction of Radiation or Chemoradiation Tx Side Effects in Patients With Prostate, Cervical, or Rectal Cancers
NCT05722288 ·Status: RECRUITING ·Phase: PHASE2
-
Nabilone Effect on the Attenuation of Anorexia, Nutritional Status and Quality of Life in Lung Cancer Patients
NCT02802540 ·Status: UNKNOWN ·Phase: PHASE2/PHASE3
-
Anamorelin Hydrochloride in Reducing Anorexia in Patients With Advanced Non-small Cell Lung Cancer
NCT03637816 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2/PHASE3
-
Safety, Tolerance and Efficacy of an Oral Nutritional Supplement in Lung Cancer Patients
NCT00851448 ·Status: TERMINATED ·Phase: NA
-
Amifostine, Chemotherapy, and Radiation Therapy in Treating Patients With Limited-Stage Small Cell Lung Cancer
NCT00004176 ·Status: COMPLETED ·Phase: PHASE2
-
Transdermal Methylphenidate for Cancer-Related Fatigue
NCT01124500 ·Status: WITHDRAWN ·Phase: NA
-
Trial of a Sustained Release Methylphenidate in the Treatment of Fatigue in Cancer Patients
NCT00516269 ·Status: TERMINATED ·Phase: PHASE3
-
Creatine in Treating Patients With Cancer-Associated Weight Loss
NCT00081250 ·Status: COMPLETED ·Phase: PHASE3
-
Single Agent Armodafinil for Patient-Reported Fatigue Following Radiation Therapy for Head and Neck Cancer
NCT01330446 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Fenretinide in Treating Patients With Metastatic or Unresectable Malignant Solid Tumors
NCT00387504 ·Status: COMPLETED ·Phase: PHASE1
-
Placebo Controlled, Randomized Safety and Efficacy Study of RC-1291 in Cancer Anorexia/Cachexia
NCT00378131 ·Status: COMPLETED ·Phase: PHASE2
-
Nutrition and Pharmacological Algorithm for Oncology Patients Study
NCT04155008 ·Status: TERMINATED ·Phase: PHASE4
-
Fasting-mimicking Diet With Chemo-immunotherapy in Non-small Cell Lung Cancer (NSCLC)
NCT03700437 ·Status: COMPLETED ·Phase: NA
-
Armodafinil in Treating Fatigue Caused By Radiation Therapy in Patients With Primary Brain Tumors
NCT01032200 ·Status: COMPLETED ·Phase: PHASE2
-
Patient Controlled Administration of Methylphenidate for Cancer Related Fatigue - PRN Methylphenidate
NCT02361125 ·Status: COMPLETED ·Phase: PHASE1
-
Adenosine Triphosphate in Treating Patients With Advanced Solid Tumors
NCT00014248 ·Status: COMPLETED ·Phase: PHASE1
-
Placebo Controlled, Randomized Safety and Efficacy Study of RC-1291 in Cancer Anorexia/Cachexia.
NCT00267358 ·Status: COMPLETED ·Phase: PHASE2
-
Medical Nutrition Therapy or Standard Care in Treating Patients With Lung Cancer, Pancreatic Cancer, or Stage III or Stage IV Prostate Cancer
NCT00769652 ·Status: TERMINATED ·Phase: NA
-
Enteral Nutrition With L-Carnitine for Cachexia in Non-Small Cell Lung Cancer
NCT07035444 ·Status: NOT_YET_RECRUITING ·Phase: NA
-
Open Labeled Placebo in Reducing Cancer Related Fatigue in Patients With Advanced Cancer
NCT03927885 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2/PHASE3