MedTrace Logo

AERs in Aphasia: Severity and Improvement

NCT00013442 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 20

Last updated 2009-01-21

No results posted yet for this study

Summary

Over one million persons in the United States are aphasic subsequent to a stroke. Most of the individuals improve through spontaneous recovery and treatment. However, there are no precise methods for predicting which patients will improve and, for those who do, how much improvement will occur. There is a need to improve prognostic precision in aphasia. The purpose of this investigation is to test the precision of auditory evoked responses (AERs) to provide a prognosis for improvement in aphasia subsequent to a left hemisphere thromboembolic infarct. We hypothesize that the presence, absence, and pattern of the AER responses will predict severity of aphasia and prognosis for improvement. Phonemic, phonologic, semantic, and syntactic language tasks will be used to elicit AERs, including the auditory late response, the mismatch negativity response (MMN), the N400, and the P600.

Conditions

Interventions

PROCEDURE

Auditory Evoked Response

Sponsors & Collaborators

Principal Investigators

  • John Fryer, Ph.D., Asst. Director · Department of Veterans Affairs, Program Analysis and Review Section (PARS), Rehabilitation Research & Development Service

  • Nancy Rocheleau, Program Analyst · Department of Veterans Affairs, Program Analysis and Review Section (PARS), Rehabilitation Research & Development Service

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2000-01-31
Completion
2002-12-31

Countries

  • United States

Study Locations

More Related Trials

Entities

Diseases
Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00013442 on ClinicalTrials.gov