Combination Chemotherapy Plus Radiation Therapy With or Without Fluorouracil in Treating Patients With Cancer of the Esophagus or Stomach
NCT00009880 · Status: COMPLETED · Phase: PHASE2 · Type: INTERVENTIONAL
Last updated 2013-07-19
Summary
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Radiation therapy uses high-energy x-rays to damage tumor cells. Combining chemotherapy and radiation therapy may kill more tumor cells.
PURPOSE: Randomized phase II trial to compare the effectiveness of combination chemotherapy plus radiation therapy with and without fluorouracil in treating patients who have cancer of the esophagus or stomach.
Conditions
- Esophageal Cancer
- Gastric Cancer
Interventions
- BIOLOGICAL
- DRUG
- DRUG
- DRUG
- RADIATION
-
radiation therapy
Sponsors & Collaborators
-
National Cancer Institute (NCI)
collaborator NIH -
Radiation Therapy Oncology Group
lead NETWORK
Principal Investigators
-
Jaffer A. Ajani, MD · M.D. Anderson Cancer Center
Study Design
- Purpose
- TREATMENT
Eligibility
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2001-04-30
- Primary Completion
- 2006-07-31
Countries
- United States
Study Locations
More Related Trials
-
Pre-operative Chemotherapy and Radiation Therapy for Esophageal Carcinoma
NCT00230451 ·Status: COMPLETED ·Phase: PHASE2
-
Combination Chemotherapy, Radiation Therapy and Surgery in Treating Patients With Cancer of the Esophagus
NCT00003087 ·Status: COMPLETED ·Phase: PHASE2
-
Chemotherapy and Radiation Therapy in Treating Patients With Cancer of the Esophagus
NCT00002884 ·Status: UNKNOWN ·Phase: PHASE3
-
Docetaxel, Oxaliplatin, Capecitabine, Fluorouracil, and Radiation Therapy in Treating Patients With Locally Advanced Cancer of the Esophagus or Gastroesophageal Junction
NCT00938470 ·Status: COMPLETED ·Phase: PHASE2
-
Combination Chemotherapy Plus Radiation Therapy Followed By Surgery in Treating Patients With Stage I, Stage II, or Stage III Esophageal Cancer
NCT00006472 ·Status: TERMINATED ·Phase: PHASE2
-
Combination Chemotherapy and Radiation Therapy in Treating Patients With Cancer of the Esophagus
NCT00002711 ·Status: COMPLETED ·Phase: PHASE1
-
Combination Chemotherapy Plus Radiation Therapy in Treating Patients With Cancer of the Esophagus
NCT00002631 ·Status: COMPLETED ·Phase: PHASE3
-
Combination Chemotherapy Plus Radiation Therapy in Treating Patients With Esophageal Cancer
NCT00005638 ·Status: COMPLETED ·Phase: PHASE1
-
Radiation Therapy + Combination Chemotherapy as 1st-Line Therapy for Patients With Inoperable Esophageal Cancer
NCT00861094 ·Status: COMPLETED ·Phase: PHASE2/PHASE3
-
Oxaliplatin, Fluorouracil, Erlotinib Hydrochloride, and Radiation Therapy Before Surgery and Erlotinib Hydrochloride After Surgery in Treating Patients With Locally Advanced Cancer of the Esophagus or Gastroesophageal Junction
NCT01561014 ·Status: COMPLETED ·Phase: PHASE1
-
Radiation Therapy, Paclitaxel, and Carboplatin With or Without Trastuzumab in Treating Patients With Esophageal Cancer
NCT01196390 ·Status: COMPLETED ·Phase: PHASE3
-
Radiation Therapy and Chemotherapy Before and After Surgery in Treating Patients With Esophageal Cancer
NCT00033657 ·Status: COMPLETED ·Phase: PHASE2
-
Oxaliplatin-Based Chemotherapy and Chemoradiotherapy or Chemoradiotherapy in Esophageal or Gastroesophageal Carcinoma
NCT00525915 ·Status: COMPLETED ·Phase: PHASE2
-
Surgery With or Without Chemotherapy and Radiation Therapy in Treating Patients With Cancer of the Esophagus
NCT00003118 ·Status: COMPLETED ·Phase: PHASE3
-
A Trial of ZD6474, Paclitaxel, Carboplatin, 5-Fluorouracil, and Radiation Therapy Followed by Surgery
NCT01183559 ·Status: COMPLETED ·Phase: PHASE1
-
Docetaxel, Cisplatin, and Radiation Therapy in Treating Patients With Locally Advanced Esophageal Cancer That Cannot Be Removed By Surgery
NCT00238407 ·Status: COMPLETED ·Phase: PHASE2
-
S0414 Cetuximab, Combo Chemo, and RT in Locally Advanced Esophageal Cancer
NCT00109850 ·Status: TERMINATED ·Phase: PHASE2
-
Combination Chemotherapy and Radiation Therapy in Treating Patients Who Are Undergoing Surgery for Locally Advanced Esophageal Cancer
NCT00238147 ·Status: COMPLETED ·Phase: PHASE1
-
Pralatrexate and Docetaxel in Treating Patients With Stage IV Esophageal or Gastroesophageal Cancer Who Have Failed Platinum-Based Therapy
NCT01129206 ·Status: COMPLETED ·Phase: PHASE2
-
Combination Chemotherapy and Radiation Therapy in Treating Patients With Esophageal Cancer or Gastroesophageal Junction Cancer
NCT00281788 ·Status: COMPLETED ·Phase: PHASE1
-
Radiation Therapy and Combination Chemotherapy With or Without Surgery in Treating Patients With Locally Advanced Esophageal Cancer That Can Be Removed By Surgery
NCT00416858 ·Status: COMPLETED ·Phase: PHASE3
-
Paclitaxel, Cisplatin, Gefitinib, and Radiation Therapy Followed by Surgery and Gefitinib in Treating Patients With Locally Advanced Cancer of the Esophagus or Gastroesophageal Junction That Can Be Removed By Surgery
NCT00493025 ·Status: TERMINATED ·Phase: PHASE2
-
A Phase III Study of Comparing Paclitaxel Plus 5-Fluorouracil Versus Cisplatin Plus 5-Fluorouracil in Chemoradiotherapy for Locally Advanced Esophageal Carcinoma
NCT01591135 ·Status: COMPLETED ·Phase: PHASE3
-
Combination Chemotherapy in Treating Patients With Esophageal Cancer
NCT00041262 ·Status: UNKNOWN ·Phase: PHASE3
-
Combination Chemotherapy, Radiation Therapy and Surgery for Esophageal Cancer
NCT00165490 ·Status: COMPLETED ·Phase: PHASE2