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Second-look Surgery With or Without Intraperitoneal Chemotherapy in Treating Patients With Recurrent Colorectal Cancer

NCT00005944 · Status: TERMINATED · Phase: PHASE2 · Type: INTERVENTIONAL

Last updated 2021-02-17

No results posted yet for this study

Summary

RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Giving chemotherapy drugs in different ways may kill more tumor cells.

PURPOSE: Randomized phase II trial to compare the effectiveness of second-look surgery with or without intraperitoneal infusions of mitomycin and fluorouracil in treating patients who have colorectal cancer that is recurrent to the peritoneum.

Conditions

Interventions

DRUG

chemotherapy

DRUG

fluorouracil

DRUG

leucovorin calcium

DRUG

mitomycin C

PROCEDURE

conventional surgery

PROCEDURE

laparoscopic surgery

Sponsors & Collaborators

  • UNICANCER

    lead OTHER

Principal Investigators

  • Dominique Elias, MD · Gustave Roussy, Cancer Campus, Grand Paris

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT

Eligibility

Min Age
0 Years
Max Age
70 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
1999-07-01
Primary Completion
2000-10-24
Completion
2003-10-01

Countries

  • Belgium
  • France

Study Locations

More Related Trials

Entities

Drugs
Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00005944 on ClinicalTrials.gov