Intravenous Compared With Intrahepatic Chemotherapy in Treating Patients With Colorectal Cancer Metastatic to the Liver
NCT00002692 · Status: UNKNOWN · Phase: PHASE3 · Type: INTERVENTIONAL · Enrollment: 312
Last updated 2013-12-19
Summary
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one drug may kill more tumor cells.
PURPOSE: Randomized phase III trial to compare the effectiveness of intravenous infusion or intrahepatic infusion of fluorouracil and leucovorin in treating patients with colorectal cancer metastatic to the liver.
Conditions
Interventions
- DRUG
- DRUG
-
isolated perfusion
- DRUG
-
leucovorin calcium
Sponsors & Collaborators
- lead OTHER_GOV
Principal Investigators
-
David J. Kerr, MD, FRCP, DSc · University Hospital Birmingham
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
Eligibility
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 1994-12-31
Countries
- United Kingdom
Study Locations
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