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Combination Chemotherapy With or Without Irinotecan in Treating Patients With Stage III Colon Cancer

NCT00005979 · Status: COMPLETED · Phase: PHASE3 · Type: INTERVENTIONAL

Last updated 2021-02-17

No results posted yet for this study

Summary

RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one drug may kill more tumor cells. It is not yet known if combination chemotherapy is more effective with or without irinotecan in treating colon cancer.

PURPOSE: Randomized phase III trial to compare the effectiveness of combination chemotherapy with or without irinotecan in treating patients who have stage III colon cancer.

Conditions

Interventions

DRUG

FOLFIRI regimen

DRUG

fluorouracil

DRUG

irinotecan hydrochloride

DRUG

leucovorin calcium

Sponsors & Collaborators

  • Federation Francophone de Cancerologie Digestive

    collaborator OTHER

  • UNICANCER

    lead OTHER

Principal Investigators

  • Marc Ychou, MD, PhD · Institut du Cancer de Montpellier - Val d'Aurelle

  • Jean Faivre · Federation Francophone de Cancerologie Digestive

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT

Eligibility

Min Age
18 Years
Max Age
75 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
1998-07-22
Primary Completion
2005-09-26
Completion
2007-09-01

Countries

  • France

Study Locations

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Entities

Drugs
Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00005979 on ClinicalTrials.gov