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Phase II Study of Lactulose and Circadian Rhythms in Patients With Cirrhosis

NCT00004796 · Status: COMPLETED · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 16

Last updated 2005-06-24

No results posted yet for this study

Summary

OBJECTIVES: I. Assess the effect of lactulose on the circadian rhythm of plasma melatonin in patients with subclinical hepatic encephalopathy.

II. Assess the intrasubject variability of circadian melatonin levels and neuropsychological tests.

III. Assess which elements of the neuropsychological test battery show the response to lactulose.

Conditions

  • Portal Hypertension
  • Hepatic Encephalopathy
  • Cirrhosis

Interventions

DRUG

lactulose

Sponsors & Collaborators

Principal Investigators

  • Andres Blei · Northwestern University

Study Design

Purpose
TREATMENT

Eligibility

Min Age
0 Years
Max Age
64 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
1994-11-30
Completion
1997-02-28

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00004796 on ClinicalTrials.gov