Study of Prevalence and Clinical Phenotype in Patients With Glucocorticoid-Remediable Aldosteronism
NCT00004354 · Status: COMPLETED · Type: OBSERVATIONAL
Last updated 2005-06-24
Summary
OBJECTIVES: I. Determine the prevalence of glucocorticoid-remediable aldosteronism (GRA) in various hypertensive populations and screen at risk members of GRA pedigrees.
II. Investigate other factors regulating blood pressure in GRA (environmental, genetically determined factors).
III. Investigate renal and hormonal mechanisms regulating potassium homeostasis in GRA.
IV. Describe clinical phenotype of GRA patients. V. Prospectively screen GRA-affected patients with MRI angiography for intracranial aneurysm.
Conditions
- Hyperaldosteronism
Sponsors & Collaborators
-
Brigham and Women's Hospital
collaborator OTHER -
National Center for Research Resources (NCRR)
lead NIH
Principal Investigators
-
Robert G. Dluhy · Brigham and Women's Hospital
Eligibility
- Min Age
- 0 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 1999-06-30
Countries
- United States
Study Locations
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