Study of Prevalence and Clinical Phenotype in Patients With Glucocorticoid-Remediable Aldosteronism

NCT00004354 · Status: COMPLETED · Type: OBSERVATIONAL

Last updated 2005-06-24

No results posted yet for this study

Summary

OBJECTIVES: I. Determine the prevalence of glucocorticoid-remediable aldosteronism (GRA) in various hypertensive populations and screen at risk members of GRA pedigrees.

II. Investigate other factors regulating blood pressure in GRA (environmental, genetically determined factors).

III. Investigate renal and hormonal mechanisms regulating potassium homeostasis in GRA.

IV. Describe clinical phenotype of GRA patients. V. Prospectively screen GRA-affected patients with MRI angiography for intracranial aneurysm.

Conditions

  • Hyperaldosteronism

Sponsors & Collaborators

  • Brigham and Women's Hospital

    collaborator OTHER
  • National Center for Research Resources (NCRR)

    lead NIH

Principal Investigators

  • Robert G. Dluhy · Brigham and Women's Hospital

Eligibility

Min Age
0 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
1999-06-30

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00004354 on ClinicalTrials.gov