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Chemotherapy in Treating Patients With Newly Diagnosed Chronic Lymphocytic Leukemia

NCT00004218 · Status: COMPLETED · Phase: PHASE3 · Type: INTERVENTIONAL

Last updated 2013-12-18

No results posted yet for this study

Summary

RATIONALE: Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. It is not yet known which regimen of chemotherapy is more effective for chronic lymphocytic leukemia.

PURPOSE: This randomized phase III trial is studying chlorambucil to see how well it works compared to fludarabine and cyclophosphamide or fludarabine alone in treating patients with newly diagnosed chronic lymphocytic leukemia.

Conditions

Interventions

DRUG

chlorambucil

DRUG

cyclophosphamide

DRUG

doxorubicin hydrochloride

DRUG

fludarabine phosphate

DRUG

prednisolone

DRUG

vincristine sulfate

Sponsors & Collaborators

Principal Investigators

  • Daniel Catovsky, MD · Royal Marsden NHS Foundation Trust

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT

Eligibility

Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
1999-10-31
Completion
2007-07-31

Countries

  • Argentina
  • Croatia
  • Greece
  • Ireland
  • Italy
  • New Zealand
  • Russia
  • United Kingdom

Study Locations

More Related Trials

Entities

Drugs
Diseases
Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00004218 on ClinicalTrials.gov