Combination Chemotherapy in Treating Patients With Chronic Myelogenous Leukemia or Recurrent Acute Leukemia
NCT00002693 · Status: COMPLETED · Phase: PHASE1 · Type: INTERVENTIONAL
Last updated 2011-08-03
Summary
RATIONALE: Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. Combining more than one drug may kill more cancer cells.
PURPOSE: Phase I trial to study the effectiveness of combination chemotherapy with carboplatin and topotecan in treating patients with chronic myelogenous leukemia or recurrent acute leukemia.
Conditions
Interventions
- BIOLOGICAL
- DRUG
- DRUG
-
topotecan hydrochloride
Sponsors & Collaborators
-
National Cancer Institute (NCI)
collaborator NIH - lead OTHER
Principal Investigators
-
Scott H. Kaufmann, MD, PhD · Mayo Clinic
Study Design
- Purpose
- TREATMENT
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 1995-10-31
- Primary Completion
- 2006-04-30
- Completion
- 2006-04-30
Countries
- United States
Study Locations
More Related Trials
-
Combination Chemotherapy in Treating Patients With Newly Diagnosed Acute Myeloid Leukemia
NCT00274807 ·Status: COMPLETED ·Phase: PHASE2
-
Comparison of Three Treatment Regimens in Treating Patients With Relapsed or Refractory Acute Myelogenous Leukemia
NCT00005962 ·Status: COMPLETED ·Phase: PHASE2
-
Mitomycin and Mitoxantrone in Treating Patients With Acute Myelogenous Leukemia
NCT00003003 ·Status: COMPLETED ·Phase: PHASE1
-
Combination Chemotherapy and Alemtuzumab in Treating Patients With Relapsed or Refractory Acute Lymphoblastic Leukemia
NCT00262925 ·Status: TERMINATED ·Phase: PHASE2
-
Treatment of Patients With Newly Diagnosed Acute Myeloid Leukemia or Myelodysplasia
NCT00136084 ·Status: COMPLETED ·Phase: PHASE3
-
Combination Chemotherapy in Treating Patients With Newly Diagnosed Acute Lymphoblastic Leukemia
NCT00016302 ·Status: COMPLETED ·Phase: NA
-
Topotecan Hydrochloride and Carboplatin With or Without Veliparib in Treating Advanced Myeloproliferative Disorders and Acute Myeloid Leukemia or Chronic Myelomonocytic Leukemia
NCT03289910 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
Combination Chemotherapy in Treating Patients With Recurrent or Refractory Leukemia or Lymphoma
NCT00047021 ·Status: COMPLETED ·Phase: PHASE2
-
Combination Chemotherapy in Treating Patients With Relapsed or Refractory Acute Lymphocytic Leukemia
NCT00002532 ·Status: UNKNOWN ·Phase: PHASE2
-
Combination Chemotherapy With or Without Filgrastim and/or Tretinoin in Treating Patients With Acute Myeloid Leukemia
NCT00005863 ·Status: COMPLETED ·Phase: PHASE3
-
Combination Chemotherapy, Biological Therapy, and Bone Marrow Transplantation in Treating Patients With Acute Myeloid Leukemia
NCT00002658 ·Status: UNKNOWN ·Phase: PHASE3
-
Combination Chemotherapy in Treating Patients With Untreated Acute Lymphoblastic Leukemia
NCT00003700 ·Status: COMPLETED ·Phase: PHASE2
-
Combination Chemotherapy With or Without Blinatumomab in Treating Patients With Newly Diagnosed BCR-ABL-Negative B Lineage Acute Lymphoblastic Leukemia
NCT02003222 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE3
-
Phase I/II Study of Mitoxantrone, Etoposide and Gemtuzumab Ozogamicin for Acute Myeloid Leukemia
NCT00660036 ·Status: TERMINATED ·Phase: PHASE1
-
Combination Chemotherapy Followed By Peripheral Stem Cell Transplantation or Isotretinoin in Treating Patients With Acute Myeloid Leukemia, Myelodysplastic Syndrome, or Acute Lymphocytic Leukemia
NCT00003619 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Chemotherapy in Treating Patients With Newly Diagnosed Acute or Chronic Myelogenous Leukemia or Myelodysplastic Syndrome
NCT00002800 ·Status: COMPLETED ·Phase: PHASE2
-
Fludarabine, Carboplatin, and Topotecan in Treating Patients With Relapsed/Refractory Acute Leukemia or Advanced Myelodysplastic Syndrome
NCT00005593 ·Status: COMPLETED ·Phase: PHASE1
-
Comparing Three Different Combination Chemotherapy Regimens in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia
NCT00634244 ·Status: COMPLETED ·Phase: PHASE2
-
Daunorubicin, Cytarabine, and Midostaurin in Treating Patients With Newly Diagnosed Acute Myeloid Leukemia
NCT00651261 ·Status: UNKNOWN ·Phase: PHASE3
-
Personalized Kinase Inhibitor Therapy Combined With Chemotherapy in Treating Patients With Newly Diagnosed Acute Myeloid Leukemia and Acute Lymphoblastic Leukemia
NCT02779283 ·Status: COMPLETED ·Phase: PHASE1
-
Comparison of Two Combination Chemotherapy Regimens in Treating Adults With Previously Untreated Leukemia or Lymphoma
NCT00002766 ·Status: COMPLETED ·Phase: PHASE3
-
Combination Chemotherapy and Tipifarnib in Treating Patients With Newly Diagnosed Acute Myeloid Leukemia
NCT00124644 ·Status: TERMINATED ·Phase: PHASE1
-
Combination Chemotherapy in Treating Patients With Acute B-Lymphoblastic Leukemia or Non-Hodgkin's Lymphoma
NCT00002471 ·Status: COMPLETED ·Phase: PHASE2
-
Combination Chemotherapy Plus Biological Therapy in Treating Patients With Acute Myelogenous Leukemia
NCT00003405 ·Status: WITHDRAWN ·Phase: PHASE2
-
Combination Chemotherapy in Treating Patients With Myelodysplastic Syndrome
NCT00003827 ·Status: UNKNOWN ·Phase: PHASE2